腰椎椎体^(99)Tc^(m)-MDPSPECT/CT定量代谢参数与患者一般资料的相关性  

Correlations of^(99)Tc^(m)-MDP SPECT/CT quantitative metabolic parameters of lumbar vertebrae with patients'general data

作　　者：郑璐 胡玉敬[1] 张新超 田丛娜[1] 李康 蔡晓雨 刘家乐 边艳珠[1,2] ZHENG Lu;HU Yujing;ZHANG Xinchao;TIAN Congna;LI Kang;CAI Xiaoyu;LIU Jiale;BIAN Yanzhu(Department of Nuclear Medicine,Hebei General Hospital,Shijiazhuang 050051,China;Hebei Provincial Key Laboratory of Cerebral Networks and Cognitive Disorders,Shijiazhuang 050051,China)

机构地区：[1]河北省人民医院核医学科,河北石家庄050051 [2]河北省脑网络与认知障碍疾病重点实验室,河北石家庄050051

出　　处：《中国医学影像技术》2023年第11期1706-1709,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察腰椎椎体^(99)Tc^(m)-亚甲基二膦酸盐(MDP)SPECT/CT定量代谢参数与患者一般资料的相关性。方法前瞻性对45例(男22例、女23例)未累及腰椎的恶性肿瘤患者行全身骨显像及腰椎SPECT/CT,在SPECT/CT图中于腰椎处放置感兴趣区容积(VOI),获得最大标准摄取值(SUVmax)、平均标准摄取值(SUVmean)、骨代谢总体积(MBV)及骨摄取总量(TBU);采用Pearson相关性分析观察腰椎椎体代谢参数与患者一般资料,包括年龄、身高及体质量的相关性。结果腰椎椎体SUVmax与患者身高、体质量及年龄均呈正相关(r=0.196、0.189、0.227,P均<0.05);SUVmean与身高、年龄呈正相关(r=0.135、0.133,P均<0.05),与体质量无明显相关性(P>0.05);MBV(r=0.221、0.583、0.410)、TBU(r=0.205、0.441、0.280)与年龄、身高及体质量均呈正相关(P均<0.05)。男性与女性腰椎椎体SUVmax、MBV及TBU差异均有统计学意义(P均<0.05),而SUVmean差异无统计学意义(P>0.05)。结论腰椎椎体^(99)Tc^(m)-MDP SPECT/CT定量代谢参数与年龄、性别及体质量相关。Objective To observe the correlations of^(99)Tc^(m)-methylene diphosphonate(MDP)SPECT/CT quantitative metabolic parameters of lumbar vertebrae with patients'general data.Methods A total of 45 malignant tumor patients(22 males and 23 females)without bone involvement were prospectively enrolled,and whole body bone imaging and lumbar spine SPECT/CT were performed.Based on SPECT/CT images,the volumes of interest(VOI)were placed on lumbar vertebrae,and the maximum standard uptake value(SUV max),mean standard uptake value(SUV mean),metabolic bone volume(MBV)and total bone uptake(TBU)were measured.Pearson correlation analysis was used to observe the correlations of metabolic parameters of lumbar vertebrae with patients'general data,including age,height and body mass.Results SUV max of lumbar vertebrae were positively correlated with height,body mass and age(r=0.196,0.189,0.227,all P<0.05),while SUV mean were positively correlated with height and age(r=0.135,0.133,both P<0.05)but not significantly correlated with body mass(P>0.05).MBV(r=0.221,0.583,0.410)and TBU(r=0.205,0.441,0.280)of lumbar vertebrae were all positively correlated with age,height and body mass(all P<0.05).There were significant differences of SUV max,MBV and TBU of lumbar vertebrae between males and females(all P<0.05),but not of SUV mean(P>0.05).Conclusion^(99)Tc^(m)-MDP SPECT/CT quantitative metabolic parameters of lumbar vertebrae were related to patients'age,gender and body mass.

关 键 词：腰椎 体层摄影术 发射型计算机 单光子 前瞻性研究 

分 类 号：R681.5[医药卫生—骨科学] R817.4[医药卫生—外科学]