复方芩兰口服液联合头孢呋辛治疗小儿急性上呼吸道感染的有效性及耐药性分析  

Efficacy and Resistance Analysis of Compound Qinlan Oral Solution Combined with Cefuroxime in Pediatric Acute Upper Respiratory Tract Infection

作　　者：薛刚 高佳 Xue Gang;Gao Jia(Pharmacy Department,Huairou Maternal and Child Health Care Hospital,Beijing Maternity Hospital affiliated to Capital Medical University,Beijing 101400,China;Pharmacy Department of Beijing Huairou Hospital,Beijing 101400,China)

机构地区：[1]首都医科大学附属北京妇产医院怀柔妇幼保健院药剂科,北京1014001 [2]北京怀柔医院药剂科,北京1014002

出　　处：《罕少疾病杂志》2023年第11期39-40,66,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的分析小儿急性上呼吸道感染患者服用复方芩兰口服液、头孢呋辛联合治疗的有效性及耐药性分析。方法对该院收治的120例患者进行诊断,被确诊为急性上呼吸道感染后进行治疗,时间段限定为2022年04月—2021年02月。随机分为两组,每组60例患者,对照组采用头孢呋辛治疗,观察组采取头孢呋辛+复方芩兰口服液治疗。对两组患者的临床效果、中医证候积分、肺功能、炎症水平进行对比。结果观察组与对照组总有效率对比,95.00%,高于78.33%,差异有统计学意义(P<0.05)。观察组患者中医证候积分较对照组更低,差异有统计学意义(P<0.05)。观察组患者肺功能指标较对照组更高,差异有统计学意义(P<0.05)。观察组炎症因子水平较对照组更低,差异有统计学意义(P<0.05)。结论患有急性上呼吸道感染的患儿通过头孢呋辛、复方芩兰口服液治疗后,治疗效果显著,能有效改善呼吸功能,减少炎症反应,具有较高的临床应用价值。Objective To analyze the efficacy and drug resistance of compound Qinlan oral liquid combined with cefuroxime in children with acute upper respiratory tract infection.Methods 120 patients admitted to the hospital were diagnosed and treated after being diagnosed with acute upper respiratory tract infection,and the time period was limited to April 2022-February 2021.They were randomly divided into two groups with 60 patients in each group.The control group was treated with cefuroxime,and the observation group was treated with cefuroxime+compound Qinlan oral liquid.The clinical effect,TCM syndrome score,lung function and inflammation level of the two groups were compared.Results The total effective rate of observation group and control group was 95.00%,higher than 78.33%,the difference was statistically significant(P<0.05).The TCM syndrome score of observation group was lower than that of control group,and the difference was statistically significant(P<0.05).The pulmonary function index of observation group was higher than that of control group,and the difference was statistically significant(P<0.05).The level of inflammatory factors in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The therapeutic effect of cefuroxime and compound Qinlan oral liquid in children with acute upper respiratory tract infection is significant,which can effectively improve respiratory function and reduce inflammation,and has high clinical application value.

关 键 词：急性上呼吸道感染 头孢呋辛 复方芩兰口服液 

分 类 号：R974[医药卫生—药品]