低剂量与常规剂量CT在肺磨玻璃影结节鉴别和浸润性诊断中的应用比较  

Comparison of Low-dose CT an d Conventional Dose CT in the Differentiation and Invasive Diagnosis of Pulmonary Ground Glass Nodules

作　　者：刘志敏[1] 祁佩红[1] LIU Zhi-min;QI Pei-hong(Department of Medical Imaging,Zhengzhou People's Hospital,Zhengzhou 450000,Henan Province,China)

机构地区：[1]郑州人民医院医学影像科,河南郑州450000

出　　处：《中国CT和MRI杂志》2023年第11期47-49,共3页Chinese Journal of CT and MRI

基　　金：河南省医学科技攻关联合共建项目(LHGJ20191092)。

摘　　要：目的探讨低剂量与常规剂量CT在肺孤立性磨玻璃影结节(GGN)鉴别和浸润性诊断中的应用。方法选取2021年1月至2021年12月在郑州人民医院就诊的120例孤立性GGN患者作为研究对象,均进行低剂量与常规剂量CT扫描检查;比较两种方式在GGN形态学特征检出率、良恶性鉴别及浸润性诊断性能上的差异;比较两种扫描方式的图像质量及扫描辐射剂量差异。结果低剂量与常规剂量CT扫描在GGN的形态学特征(分叶征、毛刺征、空洞征、钙化、血管集束征及胸膜凹陷征)检出率及图像质量等级上均无统计学差异(P>0.05);低剂量CT鉴别GGN良恶性的敏感度、特异性和准确度分别为84.48%、90.32%和87.50%,略低于常规剂量CT的91.38%、93.55%和92.50%;低剂量CT诊断GGN浸润性的敏感度、特异性和准确度分别为76.00%、75.76%和75.86%,低于常规剂量CT的92.00%、90.91%和91.38%。低剂量CT的剂量长度乘积,CT容积剂量指数、有效剂量及有效管球剂量均显著低于常规CT扫描(P<0.05)。结论低剂量与常规剂量CT扫描鉴别肺孤立性GGN良恶性的性能相当,但常规剂量CT对GGN浸润性的诊断性能相对较高,而低剂量CT辐射剂量更低。Objective To investigate the application of low-dose and conventional dose CT in the differentiation and invasive diagnosis of pulmonary ground glass nodules(GGN).Methods 120 solitary GGN patients who admitted to Zhengzhou People's Hospital from January 2021 to December 2021 were collected as the study subjects,and low-dose and conventional dose CT examinations were performed;The performance of the two methods in morphological feature detection rate,benign and malignant differentiation and invasive diagnosis of GGN was compared;The image quality and radiation dose of the two scanning methods were compared.Results There was no statistically significant differences between low-dose and conventional dose CT scans in morphological characteristics of GGN(lobulation sign,burr sign,cavity sign,calcification,vascular cluster sign and pleural depression sign)and image quality grade(P>0.05);The sensitivity,specificity and accuracy of low-dose CT in differentiating GGN from benign to malignant were 84.48%,90.03%and 87.50%,respectively,slightly lower than that of conventional CT(93.38%,93.55%and 92.50%,respectively).The sensitivity,specificity and accuracy of low-dose CT in diagnosing GGN infiltration were 76.00%,75.76%and 75.86%,respectively,lower than that of conventional CT(92.00%,90.91%and 91.37%).The dose length product,volumetric dose index,effective dose and effective ball dose of low-dose CT were significantly lower than those of conventional CT(P<0.05).Conclusion The Lowdose and conventional dose CT scans have the same performance in differentiating benign and malignant pulmonary isolated GGN,but conventional dose CT has a relatively higher performance in diagnosing GGN invasion,while low-dose CT has a lower radiation dose.

关 键 词：低剂量CT 常规剂量CT 肺磨玻璃影结节 浸润性 诊断 

分 类 号：R563[医药卫生—呼吸系统]