宫颈小细胞神经内分泌癌的磁共振表现  

Magnetic Resonance Findings of Small Cell Neuroendocrine Carcinoma of the Cervix

作　　者：任旺 郑祥[1] 苏丽清 马宁[1] Ren Wang;Zheng Xian;Su Li-qing;Ma Ning(Department of Radiological Diagnosis,Clinical Oncology School of Fujian Medical University,Fujian Cancer Hospital,Fuzhou 350014,Fujian Province,China)

机构地区：[1]福建医科大学肿瘤临床医学院,福建省肿瘤医院放诊科,福建福州350014

出　　处：《中国CT和MRI杂志》2023年第11期114-116,共3页Chinese Journal of CT and MRI

基　　金：福建省自然科学基金资助项目(2023J011283)。

摘　　要：目的分析宫颈小细胞神经内分泌癌(small cell neuroendocrine carcinoma of the uterine cervix,SCNECC)的磁共振(MRI)表现。方法收集SCNECC患者22例、宫颈鳞癌20例,分析SCNECC的临床及病理特点、MRI表现,并测量表观扩散系数(ADC),比较两组之间的ADC值差异。结果SCNECC组平均发病年龄明显低于宫颈鳞癌(48.68 vs 62.65,P=0.00)。MRI上表现为T2WI均匀/不均匀高信号,部分病灶(9/22)内可见小片状更高T2WI信号区,增强扫描呈不均匀中等强化,以病灶周围强化明显,可见明显强化的纤维间隔。弥散加权成像(DWI)上呈明显高信号,鳞癌平均ADC值为(0.99±0.21)×10^(-3)mm^(2)/s,SCNECC平均ADC值为(0.63±0.20)×10^(-3)mm^(2)/s,两者的差异具有统计学意义(P=0.00)。复合性SCNECC与单纯性SCNECC的ADC值无明显差异(P=0.19)。结论SCNECC发病年龄较鳞癌低,MRI上T2WI及增强序列具有一定的特征性,ADC值有助于鉴别SCNECC与宫颈鳞癌。Objective To analyze the magnetic resonance imaging(MRI)findings of small cell neuroendocrine carcinoma of the uterine cervix(SCNECC).Methods 22 patients with SCNECC and 20 patients with cervical squamous cell carcinoma were collected.The clinical and pathological features and MRI manifestations of SCNE CC were analyzed.The apparent diffusion coefficient(ADC)was measured and the difference of ADC value between the two groups was compared.Results The average age of onset in SCNE CC group was significantly lower than that in cervical squamous cell carcinoma group(48.68 vs 62.65,P=0.00).MRI showed homogeneous/heterogeneous hyperintensity on T2WI,small patches of higher T2WI signal area were seen in some lesions(9/22),and uneven moderate enhancement was observed on enhancement scan,with obvious enhancement around the lesion and obvious enhanced fiber septum.The mean ADC value of squamous cell carcinoma was(0.99±0.21)×10^(-3)mm^(2)/s,and the mean ADC value of SCNE CC was(0.63±0.20)×10^(-3)mm^(2)/s,and the difference was statistically significant(P=0.00).There was no significant difference in ADC value between complex SCNE CC and simple SCNE CC(P=0.19).Conclusion The age of onset of SCNE CC is lower than that of SCNE CC.T2WI and enhanced sequence on MRI have certain characteristics.ADC value is helpful to distinguish SCNECC from cervical squamous cell carcinoma.

关 键 词：宫颈肿瘤 小细胞神经内分泌癌 磁共振弥散加权成像 表观弥散系数 

分 类 号：R711.74[医药卫生—妇产科学] R445.2[医药卫生—临床医学]