补肾壮骨膏方治疗肝肾亏虚型股骨颈骨折临床研究  

Clinical Study on Kidney-Tonifying and Bone-Strengthening Ointment in the Treatment of Femur Neck Fracture with Liver-Kidney Deficiency Syndrome

作　　者：张雪 李越[1] 刘胜贵 王功国[1] ZHANG Xue;LI Yue;LIU Shenggui;WANG Gongguo(Rizhao Traditional Chinese Medicine Hospital,Rizhao,Shandong,China,276800)

机构地区：[1]日照市中医医院,山东日照276800

出　　处：《河南中医》2023年第11期1715-1720,共6页Henan Traditional Chinese Medicine

基　　金：山东省中医药科技项目(20212013)。

摘　　要：目的:观察补肾壮骨膏方治疗肝肾亏虚型股骨颈骨折的临床疗效。方法:选取2016年5月至2020年5月在日照市中医医院创伤骨科行手术治疗的46例肝肾亏虚型股骨颈骨折患者为研究对象,按照随机数字表法分为治疗组和对照组,每组各23例。治疗组给予补肾壮骨膏方服用,对照组给予仙灵骨葆胶囊口服。比较两组患者的临床疗效、骨折愈合时间、髋关节Harris评分、视觉模拟疼痛(visual analogue scale, VAS)评分、生活质量评分变化情况。结果:治疗组骨折愈合时间短于对照组(P<0.05)。术后6个月、术后12个月治疗组Harris评分优于对照组,差异具有统计学意义(P<0.05),治疗组术后12个月与术后6个月比较,差异无统计学意义(P>0.05)。两组患者治疗后中医证候积分低于本组治疗前,且治疗后治疗组低于对照组(P<0.05)。治疗组显效率为82.61%,对照组显效率为56.52%,两组患者显效率比较,具有统计学意义(P<0.05)。两组患者术后6个月、术后12个月VAS评分低于本组手术前,且治疗组低于对照组,治疗组术后12个月评分低于术后6个月(P<0.05)。治疗组在术后6个月、术后12个月生活质量评分明显优于对照组,且治疗组术后12个月PCS评分高于术后6个月,差异均有统计学意义(P<0.05)。结论:补肾壮骨膏方治疗肝肾亏虚型股骨颈骨折,可加快骨折愈合速度,减轻患者疼痛程度,促进肢体功能恢复,提高生活质量。Objective:To observe the clinical efficacy of Kidney-Tonifying and Bone-Strengthening Ointment on femoral neck fracture with liver-kidney deficiency syndrome.Methods:A total of 46 patients with liver-kidney deficiency type of femoral neck fracture who un-derwent surgical treatment in the traumatic orthopedics department of Rizhao Traditional Chinese Medicine Hospital from May 2016 to May 2020 were selected as the research subjects and divided into the treatment group and the control group according to the random number table method,with 23 cases in each group.The treatment group was given Kidney-Tonifying and Bone-Strengthening Ointment,while the control group was given Xianling Gubao Capsules(仙灵骨葆胶囊,XLGBC)orally.Theclinical efficacy,fracturehealing time,hip Harris score,visual analogue scale(VAS)score and quality of life score were compared between the two groups.Results:The healing time of fracture in the treatment group was shorter than that in the control group(P<0.05).At the 6"month and the 12h month after surgery,the Harris score of the treatment group was all better than that of the control group,and the difference was statisti-cally significant(P<0.05),but there was no statistically significant difference between the treatment group at the 12th month and the 6^(th) month(P>0.05).The TCM syndrome scores of the two groups after treatment were lower than those before treatment,and the treat-ment group's scores were lower than those of the control group(P<0.05).The significant efficiency rate of the treatment group was 82.61%,and that of the control group was 56.52%,and there was statistical significance between the two groups(P<0.05).The VAS scores at the 6^(th) month and the 12^(th) month after surgery in the two groups were lower than those before surgery,and the scores at the 12^(th) month after surgery in the treatment group were lower than those in the control group,and the scores at the 12th month after sur-gery in the treatment group were lower than those at the 6^(th) month fter surgery(P

关 键 词：股骨颈骨折 肝肾亏虚证 补肾壮骨膏方 仙灵骨葆胶囊 

分 类 号：R274.983.42[医药卫生—中西医结合]