莱菔子化学成分及药理作用研究概况  

Overview of Chemical Constituents and Pharmacological Effects of Laifuzi(Raphani Semen)

作　　者：贾蔷[1] 阴启明 李运伦[1,2] 齐冬梅[1] JIA Qiang;YIN Qiming;LI Yunlun;QI Dongmei(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]山东中医药大学附属医院,山东济南250014

出　　处：《山东中医药大学学报》2023年第6期805-811,共7页Journal of Shandong University of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(编号:81974555);山东省医药卫生科技发展计划项目(编号:2019WS576)。

摘　　要：莱菔子是十字花科植物萝卜的干燥成熟种子,具有降气化痰、消食除胀之功。莱菔子的化学成分主要有生物碱类、硫苷类、挥发性成分、脂肪酸、黄酮类等,并具有增强胃肠动力、降血压、降血脂、抗癌、化痰、镇咳、平喘等药理活性。其中最主要的活性成分是芥子碱硫氰酸盐,在降血压、降血脂、抗炎、抗氧化过程中发挥着重要的药理作用。通过检索文献,分类总结了近年来国内外莱菔子化学成分及药理作用的研究报道,以期为莱菔子相关药品及保健品的研究与开发提供参考。参考文献80篇。Laifuzi(Raphani Semen)is the dry and mature seed of cruciferae plant radish,which can reduce qi and resolve phlegm,promote digestion and relieve distension.The chemical constituents of Laifuzi mainly include alkaloids,sulfides,volatile components,fatty acids and flavonoids,etc.,and have pharmacological activities such as enhancing gastrointestinal motility,lowering blood pressure,lowering blood lipids,anticancer,resolving phlegm,relieving cough and asthma,etc.The most important active ingredient is sinapine thiocyanate,which plays an important role in the process of lowering blood pressure,lowering blood lipids,anti-inflammatory and anti-oxidation.By searching the literature,the study reports on the chemical components and pharmacological effects of Laifuzi at home and abroad in recent years were summarized,so as to provide references for the research and development of related drugs and health products of Laifuzi.There are 80 references in total.

关 键 词：莱菔子 萝卜 化学成分 生物碱类 药理活性 抗氧化 增强胃肠动力 降血压 

分 类 号：R282.710.5[医药卫生—中药学]