A型肉毒毒素注射后致视力丧失的研究进展  

Research progress of vision loss after botulinum toxin A injection

作　　者：李欣欣 魏述强 马旭[1] Li Xinxin;Wei Shuqiang;Ma Xu(Plastic Surgery Department,the Second Affiliated Hospital of Harbin Medical University,Harbin 150001,China;Burn and Plastic Surgery Department,Qingdao Central Hospital,Qingdao 266041,China)

机构地区：[1]哈尔滨医科大学附属第二医院整形外科,哈尔滨150001 [2]青岛市中心医院烧伤整形科,青岛266041

出　　处：《中华整形外科杂志》2023年第10期1162-1166,共5页Chinese Journal of Plastic Surgery

基　　金：2021年黑龙江省大学生创新创业训练项目基金(S202110226046);黑龙江省卫生计生委课题(2018307);黑龙江省自然科学基金联合引导项目(LH2019H069);中国博士后科学基金面上资助项目(2019M661299)。

摘　　要：A型肉毒毒素(BTX-A)由于疗效确切、安全性高、创伤小, 在临床上得到广泛应用。注射BTX-A后可能会引起一些常见的并发症, 如表情不自然、眉畸形、上睑下垂、复视, 以及少见的过敏反应、吞咽困难及呼吸困难等。目前有文献报道注射后也会出现视力下降甚至丧失, 尽管目前相关报道极少, 但这也应该引起临床医生们的足够重视。为此, 作者回顾近年来的相关文献, 对BTX-A注射后引起视力丧失的临床表现、发病机制和治疗方法进行综述。Botulinum toxin type A(BTX-A)is widely used in clinical practice due to its precise efficacy,high safety and low invasiveness.BTX-A injections may cause some common complications,such as unnatural expression,brow deformity,ptosis,diplopia,and rare allergic reactions,dysphagia,and dyspnea.There are reports in the literature that visual loss can also occur after injection,and although there are very few relevant reports,clinicians should pay enough attention on it.To this end,the authors reviewed the relevant literature in recent years and reviewed the clinical manifestations,pathogenesis and treatment method of vision loss caused by BTX-A injection.

关 键 词：肉毒毒素类 A型 注射美容技术 并发症 视力丧失 

分 类 号：R622[医药卫生—整形外科]