组织运动二尖瓣环位移自动追踪技术评价不同程度冠状动脉病变患者左心室收缩功能  

Evaluation of Left Ventricular Systolic Function in Patients with Varying Degrees of Coronary Artery Disease Using Tissue Motion Tracking of Mitral Annular Displacement

作　　者：姚驰 葛丽丽 李鑫 王杰冰 王晶 张淑伟 刘芷宁 Yao Chi;Ge Lili;Li Xin;Wang Jiebing;Wang Jing;Zhang Shuwei;Liu Zhining(Department of Ultrasound,The First Affiliated Hospital of Jinzhou Medical University,Jinzhou Liaoning 121001,China)

机构地区：[1]锦州医科大学附属第一医院超声科,辽宁省锦州市121001

出　　处：《中国超声医学杂志》2023年第10期1117-1121,共5页Chinese Journal of Ultrasound in Medicine

基　　金：锦州医科大学-博泽青年科技人才托举项目基金资助项目(No.JYBZQT2107);辽宁省兴辽英才计划项目(No.XLYC1802049);锦州医科大学大学生创新训练项目(No.2022X086X)。

摘　　要：目的 探讨组织运动二尖瓣环位移自动追踪(TMAD)技术评价不同程度冠状动脉病变患者左心室收缩功能。方法 选取冠心病(CHD)患者90例,健康体检者40例作为对照组,根据Gensini评分将CHD患者分为3组:轻度组(1~25分)28例、中度组(26~50分)34例、重度组(>50分)28例,测量TMAD参数与实时三维超声心动图(RT-3DE)参数、所需要的时间,比较各组间TMAD参数与RT-3DE参数的差异,并探讨2种参数之间的相关性。结果 与对照组相比,轻度、中度、重度组TMAD参数逐渐减低,差异均有统计学意义(P<0.05或P<0.01),轻度组实时三维超声心动图(RT-3DE)参数与对照组相比差异没有统计学意义(P>0.05),中度、重度组RT-3DE参数差异均有统计学意义(P<0.01);与轻度组相比,中度、重度组TMAD参数及RT-3DE参数差异均有统计学意义(P<0.01);与中度组相比,重度组TMAD参数及RT-3DE参数差异均有统计学意义(P<0.01);与RT-3DE相比,TMAD分析时间明显缩短(P<0.05);TMAD参数与左室射血分数(LVEF)相关性良好(P<0.01)。结论 TMAD可识别不同程度冠状动脉病变患者左心室收缩功能障碍,为临床早期发现CHD患者心功能异常提供了一种分析简捷、快速的方法。Objective This study aims to evaluate of left ventricular systolic function in patients with different levels of coronary heart disease using tissue motion tracking of mitral annular displacement(TMAD).Methods A total of 90 patients with coronary heart disease(CHD)and 40 healthy people as the control group were selected and divided CHD patients into three groups based on the Gensini score:mild(1-25 points)with 28 patients,moderate(26-50 points)with 34 patients,and severe(>50 points)with 28 patients.TMAD parameters and real time 3-dimensional echocardiography(RT-3DE)parameters were measured,and the time required for analysis was compared.Additionally,the differences and correlation between TMAD parameters and RT-3DE parameters among the groups were explored.Results Compared to the control group,TMAD parameters gradually decreased in the mild,moderate,and severe groups,with statistical significance(P<0.05 or P<0.01).The RT-3DE parameters in the mild group were not significantly different with the control group(P>0.05),while the RT-3DE parameters in the moderate and severe groups showed statistically difference with the control group(P<0.o1).There were statistically significant differences in TMAD parameters and RT-3DE parameters between the moderate and severe groups compared to the mild group(P<o.O1).Furthermore,the severe group had statistically significant differences in TMAD parameters and RT-3DE parameters compared to the moderate group(P<0.O1).The TMAD analysis time was significantly shorter compared to RT-3DE(P<0.05).There was a good correlation between TMAD parameters and left ventricular ejection fraction(LVEF)(P<O.O1).Conclusions TMAD parameters can identify left ventricular systolic dysfunction in patients with varying degrees of coronary artery disease.This provides a simple and fast analysis method for the early detection of cardiac dysfunction in patients with coronary heart disease.

关 键 词：组织运动二尖瓣环位移自动追踪技术 冠心病 GENSINI评分 左心室收缩功能 

分 类 号：R540.45[医药卫生—心血管疾病] R541.4[医药卫生—内科学]