基于数据挖掘探讨慢性心力衰竭证候规律  

Study on Syndromes Regularity of Chronic Heart Failure Based on Data Mining Technology

作　　者：李思璇 王宇[2] 胡渊龙 李运伦[1,2] LI Sixuan;WANG Yu;HU Yuanlong;LI Yunlun(Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]山东中医药大学附属医院,山东济南250011

出　　处：《山东中医杂志》2023年第11期1186-1191,共6页Shandong Journal of Traditional Chinese Medicine

基　　金：济南“高校20条”项目(编号:2020GXRC017);山东省“泰山学者”专项基金(编号:ts201712042);山东省医药卫生科技发展计划项目(编号:202003011161)。

摘　　要：目的:探讨慢性心力衰竭的证候分布规律。方法:运用德尔菲法制定《慢性心力衰竭症状诊断量表》,并根据该量表对769例慢性心力衰竭患者的四诊信息进行数据挖掘,通过聚类分析、因子分析探究慢性心力衰竭的证候分布规律。结果:运用德尔菲法形成的《慢性心力衰竭症状诊断量表》共包含96个症状条目。针对患者四诊信息进行的因子分析显示,慢性心力衰竭的病位涉及心、脾、肝、肾、脑,病性涉及气虚、阴虚、血瘀、痰湿、阳虚;聚类分析显示,慢性心力衰竭证型包括气虚血瘀证、气阴两虚血瘀证、阳虚水泛证、痰浊壅盛证。结论:慢性心力衰竭病机特点为本虚标实,本虚以气虚、阴虚、阳虚为主,标实以瘀血、痰浊为主,最终可致气虚与阴虚、阳虚同时存在。Objective:To explore the distribution regularity of syndromes of chronic heart failure(CHF).Methods:The Delphi method was used to form the CHF Symptom Diagnosis Scale.According to the CHF Symptom Diagnosis Scale,the four diagnostic information of 769 patients with CHF was collected and mined by cluster analysis and factor analysis,so as to explore the distribution regularity of syndromes of CHF.Results:The CHF Symptom Diagnosis Scale formed by Delphi method totally included 96 symptom items.The factor analysis on the patients’four diagnostic information showed that the location of CHF mainly involved heart,spleen,liver,kidney,and brain,and the disease nature involved qi deficiency,yin deficiency,blood stasis,phlegm dampness,and yang deficiency.The cluster analysis showed that the syndrome types of CHF included qi deficiency and blood stasis syndrome,qi and yin deficiency and blood stasis syndrome,yang deficiency and water flooding syndrome,phlegm and turbid stagnation syndrome.Conclusions:The pathogenesis characteristic of CHF is deficiency in origin and excess in superficiality.The deficiency in origin consists largely of qi deficiency,yang deficiency,and yin deficiency,while the excess in superficiality consists largely of blood stasis and phlegm-turbidity,all of which can finally lead to qi deficiency going together with yin dificiency and yang deficiency.

关 键 词：慢性心力衰竭 聚类分析 因子分析 气虚 阴虚 阳虚 瘀血 痰浊 

分 类 号：R256.2[医药卫生—中医内科学]