超声弹性成像联合细针穿刺细胞学活检诊断甲状腺微小癌的临床价值  

Clinical value of ultrasound elastography combined with fine-needle aspiration cytology biopsy in the diagnosis of thyroid microcarcinoma

作　　者：赵蓉 汤四新[1] 姚钱晶 ZHAO Rong;TANG Sixin;YAO Qianjing(Department of Ultrasound,Fourth People's Hospital of Taizhou City,Taizhou,Jiangsu,225300,China)

机构地区：[1]泰州市第四人民医院超声科,江苏泰州225300

出　　处：《当代医学》2023年第21期149-152,共4页Contemporary Medicine

摘　　要：目的探究超声弹性成像联合细针穿刺细胞学活检诊断甲状腺微小癌的临床价值。方法回顾性分析2018年5月至2021年5月本院收治的92例疑似甲状腺微小癌患者的临床资料,所有患者均进行超声弹性成像、细针穿刺细胞学活检诊断。以手术病理结果为金标准,比较两种诊断方法及联合检查的漏诊率、误诊率、灵敏度、准确率及特异度。结果92例患者中,手术病理检查确诊甲状腺微小癌50例,甲状腺良性结节42例;超声弹性成像检出甲状腺微小癌40例,甲状腺良性结节12例;细针穿刺细胞学活检检出甲状腺微小癌45例,甲状腺良性结节22例;联合检查检出甲状腺微小癌49例,甲状腺良性结节37例。3种诊断方法灵敏度、特异度、准确度、漏诊、误诊比较差异有统计学意义(P<0.05)。联合检查灵敏度高于超声弹性成像,漏诊率低于超声弹性成像,差异有统计学意义(P<0.05),联合检查与细针穿刺细胞学活检,超声弹性成像与细针穿刺细胞学活检灵敏度、漏诊率比较差异无统计学意义;联合检查特异度、准确度均高于超声弹性成像、细针穿刺细胞学活检,误诊率低于超声弹性成像、细针穿刺细胞学活检,且细针穿刺细胞学活检特异度、准确度均高于超声弹性成像,误诊率低于超声弹性成像,差异有统计学意义(P<0.05)。结论超声弹性成像联合细针穿刺细胞学活检诊断甲状腺微小癌的效能更高,具有较高的临床应用价值。Objective To explore the clinical value of ultrasound elastography combined with fine-needle aspiration cytology biopsy in the diagnosis of thyroid microcarcinoma.Methods The clinical data of 92 patients with suspected thyroid microcarcinoma admitted to our hospital from May 2018 to May 2021 were retrospective analyzed,all patients were diagnosed with ultrasound elastography and fine-needle aspiration cytology biopsy.Taking the surgical pathological results as the gold standard,the missed diagnosis rate,misdiagnosis rate,sensitivity,accuracy and specificityamong the two diagnostic methods and the combined diagnosis were compared.Results Among 92 patients,50 cases of thyroid microcarcinoma and 42 cases of benign thyroid nodules were confirmed by surgical pathological examination;40 cases of thyroid microcarcinoma and 12 cases of benign thyroid noduleswere confirmed byultrasound elastography;45 cases of thyroid microcarcinoma and 22 cases of benign thyroid nodules were confirmed by fine-needle aspiration cytological biopsy.49 cases of thyroid microcarcinoma and 37 cases of benign thyroid noduleswere confirmed by combined examination.There were significant differences in sensitivity,specificity,accuracy,missed diagnosis and misdiagnosis among the three diagnostic methods(P<0.05).The sensitivity of combined examination was higher than that of ultrasound elastography,and the missed diagnosis rate was lower than that of ultrasound elastography,the differences were significant(P<0.05),there was no statistically significant difference in sensitivity and missed diagnosis rate between combined examination and fine-needle aspiration cytology biopsy,ultrasound elastography and fine-needle aspiration cytology biopsy;the specificity and accuracy of combined examination were higher than those of ultrasound elastography and fine-needle aspiration cytology biopsy,and the misdiagnosis rate of combined examination was lower than that of ultrasound elastography and fine-needle aspiration cytology biopsy,and the specificity and accur

关 键 词：超声弹性成像 细针穿刺细胞学活检 甲状腺微小癌 灵敏度 特异度 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]