头孢米诺钠治疗社区获得性肺炎的临床效果观察  

Effect of Cefminol Sodium Therapy on Adverse Effects,Pathogen Clearance and Total Response Rate in Patients with Community-Acquired Lung Infection

作　　者：刘歆 张美泉 王集红 LIU Xin;ZHANG Meiquan;WANG Jihong(Teaching Hospital of Fujian Medical University,Department of Respiratory and Critical Care Medicine,Fujian Elderly Hospital,Fuzhou 350000,China)

机构地区：[1]福建医科大学教学医院福建省老年医院呼吸与危重症医学科,福建福州350000

出　　处：《中国医药指南》2023年第32期21-23,共3页Guide of China Medicine

摘　　要：目的探究社区获得性肺炎患者应用头孢米诺钠取得的临床效果。方法纳入我院2021年4月至2022年3月确诊为非重症社区获得性肺炎的患者63例,选用随机数表法将其划分为两组,对照组32例、观察组31例,对照组应用莫西沙星治疗,观察组应用头孢米诺钠,对比两组患者治疗效果,评估指标包含治疗有效率、临床症状消退时间、血清炎症因子、肺功能水平和不良反应。结果观察组喘鸣音、肺部啰音、发热、咳痰等症状消退时间短于对照组(P<0.05)。治疗后,两组患者机体血清炎症因子水平均降低,且观察组低于对照组(P<0.05)。观察组治疗有效率高于对照组(P>0.05)。和对照组相比,观察组不良反应发生率较低(P<0.05)。治疗前,两组患者肺功能水平无显著差异(P>0.05);治疗后,观察组肺功能水平高于对照组(P<0.05)。结论对于非重症社区获得性肺炎,头孢米诺钠具有与莫西沙星相当的治疗有效率,不良反应比莫西沙星更少,安全性好。Objective To investigate the effectiveness of cefminox sodium in the treatment of community-acquired pneumonia.Methods The 63 patients diagnosed with non-severe community-acquired pneumonia from April 2021 to March 2022 in our hospitalwere included in this study,and were divided into two groups of 32 cases in the control group and 31 cases in the observation group by using the random number table method;the control group was treated with moxifloxacin,and the observation group was treated with cefminoxib sodium,and the treatment effects of the patients in the two groups were compared,and the indicators of the assessment included the treatment efficiency,the time of clinical symptoms subsiding,the serum inflammatory factor,the lung function level and the adverse reactions.The evaluation indexes included treatment efficiency,clinical symptoms subsiding time,serum inflammatory factor,lung function level and adverse reactions.Results In the observation group,the time for symptoms such as wheezing,lung rales,fever and coughing sputum to subside was shorter than that of the control group(P<0.05).After treatment,the serum inflammatory factor of both groups was reduced,and the observation group was lower than the control group(P<0.05).The effective rate of treatment in the observation group was higher than that in the control group(P>0.05).Compared with the control group,the incidence of adverse reactions in the observation group was lower(P<0.05).Before treatment,there was no significant difference in comparing the lung function levels of the two groups of patients(P>0.05);after taking therapeutic measures,the observation group's lung function level was higher than that of the control group(P<0.05).Conclusions For non-severe community-acquired pneumonia,cefminol sodium has an effective rate comparable to moxifloxacin,less adverse effects than moxifloxacin,and good safety.

关 键 词：头孢米诺钠 社区获得性肺炎 不良反应 肺功能 

分 类 号：R563[医药卫生—呼吸系统]