Factors influencing the sperm retrieval rate of microdissection testicular sperm extraction in patients with nonmosaic Klinefelter syndrome  

作　　者：De-Feng Liu Han Wu Zhe Zhang Kai Hong Hao-Cheng Lin Jia-Ming Mao Hui-Yu Xu Lian-Ming Zhao Hui Jiang 

机构地区：[1]Center for Reproductive Medicine,Department of Obstetrics and Gynecology,Peking University Third Hospital,Beijing 100191,China [2]Department of Urology,Peking University Third Hospital,Beijing 100191,China

出　　处：《Asian Journal of Andrology》2023年第6期704-707,共4页亚洲男性学杂志（英文版）

基　　金：This study was supported by the Natural Science Foundation of Beijing Municipality(No.7194332 and No.7222208).

摘　　要：To investigate the factors affecting the sperm retrieval rate of microdissection testicular sperm extraction(micro-TESE)in patients with nonmosaic Klinefelter syndrome(KS),64 patients with nonmosaic KS who underwent micro-TESE in the Center for Reproductive Medicine of Peking University Third Hospital(Beijing,China)between January 2016 and December 2017 were included in the study.Data on medical history,physical examination and laboratory examination results,and micro-TESE outcomes were collected.Patients were divided into two groups according to micro-TESE outcomes.The following factors were compared between the two groups by the Mann‒Whitney U test or Student’s t-test based on the distribution(nonnormal or normal)of the factors:age,testicular size,follicle-stimulating hormone level,luteinizing hormone level,testosterone level,and anti-Müllerian hormone level.The overall success rate of sperm retrieval was 50.0%.Correlation analysis showed that testicular volume was positively correlated with testosterone level.Using a logistic regression model,age and anti-Müllerian hormone levels were found to be better predictors for the sperm retrieval rate than the other parameters.

关 键 词：Klinefelter syndrome prediction model sperm retrieval rate 

分 类 号：R697[医药卫生—泌尿科学]