The effect of scrotal versus inguinal orchiopexy on the testicular function of children with clinically palpable,inguinal undescended testis:a randomized controlled trial  

作　　者：Wen-Hua Huang Long-Yao Xu Shu-Shen Chen Zhi-Qiang Chen Xu Cui Chao-Ming Zhou 

机构地区：[1]Department of Pediatric Surgery,Fujian Maternity and Child Health Hospital,College of Clinical Medicine for Obstetrics&Gynecology and Pediatrics,Fujian Medical University,Fuzhou 350005,China [2]Department of Urinary Surgery,Fujian Children’s Hospital,College of Clinical Medicine for Obstetrics&Gynecology and Pediatrics,Fujian Medical University,Fuzhou 350001,China

出　　处：《Asian Journal of Andrology》2023年第6期745-749,共5页亚洲男性学杂志（英文版）

基　　金：The authors would like to acknowledge the Provincial Health Special Subsidy Project of Fujian Provincial Finance Department(No.[2020]467).

摘　　要：To compare the impact of the scrotal vs inguinal orchidopexy approach on the testicular function of infants with cryptorchidism,a randomized controlled trial was conducted involving boys who were 6–12 months old at surgery and were diagnosed with clinically palpable,inguinal undescended testis.Between June 2021 and December 2021,these boys at Fujian Maternity and Child Health Hospital(Fuzhou,China)and Fujian Children’s Hospital(Fuzhou,China)were enrolled.Block randomization with a 1:1 allocation ratio was employed.The primary outcome was testicular function assessed by testicular volume,serum testosterone,anti-Müllerian hormone(AMH),and inhibin B(InhB)levels.Secondary outcomes included operative time,amount of intraoperative bleeding,and postoperative complications.Among 577 screened patients,100(17.3%)were considered eligible and enrolled in the study.Of the 100 children who completed the 1-year follow-up,50 underwent scrotal orchidopexy and 50 underwent inguinal orchidopexy.The testicular volume,serum testosterone,AMH,and InhB levels in both groups increased markedly after surgery(all P<0.05),but there were no apparent differences between groups at 6 months and 12 months after operation(all P>0.05).No differences between the scrotal and inguinal groups were noted regarding the operative time(P=0.987)and amount of intraoperative bleeding(P=0.746).The overall complication rate(2.0%)of the scrotal group was slightly lower than that of the inguinal group(8.0%),although this difference was not statistically significant(P>0.05).Both scrotal and inguinal orchiopexy exerted protective effects on testicular function in children with cryptorchidism,with similar operative status and postoperative complications.Scrotal orchiopexy is an effective alternative to inguinal orchiopexy in children with cryptorchidism.

关 键 词：CRYPTORCHIDISM ORCHIOPEXY SCROTUM testicular function 

分 类 号：R697[医药卫生—泌尿科学]