相分离法制备聚合物微球的研究进展  

Research Progress on the Preparation and Application of Polymeric Microspheres by Phase Separation Method

作　　者：夏厚胜 万赜祺 汤娇 汤家祥 牛俊峰 盛仲夷 路胜利 Xia Housheng;Wan Zeqi;Tang Jiao;Tang Jiaxiang;Niu Junfeng;Shen Zhongyi;Lu Shengli(Key Laboratory of Chemical and Biological Processing Technology for Farm Products of Zhejiang Province,School of Biological and Chemical Engineering,Zhejiang University of Science and Technology,Hangzhou 310023,China;Zhejiang Tiantai Xianghe Industrial Co.,Ltd.,Zhejiang Xianghe Railway Fastener Research Institute,Taizhou 317200,China)

机构地区：[1]浙江科技学院生物与化学工程学院浙江省农产品化学与生物加工技术重点实验室,杭州310023 [2]浙江天台祥和实业股份有限公司,浙江省祥和轨道扣件研究院,浙江台州317200

出　　处：《工程塑料应用》2023年第11期168-174,共7页Engineering Plastics Application

基　　金：浙江省尖兵领雁研发攻关计划项目(2022C01177)。

摘　　要：聚合物微球性能优异而受到学术和产业界广泛关注。相分离法是基于热力学和动力学原理,通过破坏不相容多组分体系的稳态平衡,从而制得聚合物微球的方法。总结了相分离法的热力学、动力学和黏弹性相分离机理,根据诱导相分离的因素不同,系统地介绍了聚合微球的具体制备方法,简述了相分离法制备聚合物微球的主要应用进展,分析了相分离法较其他常见微球制备方法的优势与不足,展望了该方法未来的研究和发展趋势。Polymer microspheres have attracted wide attention from academia and industry area due to their outstanding properties.The method of phase separation is based on thermodynamic and kinetic principles that produce polymeric microspheres by perturbing the steady-state balance of multicomponent incompatible systems.The thermodynamics,kinetics,and viscoelastic mechanism of the phase separation methods were summarized and the specific preparation methods according to the different inducing factors were systematically introduced.The applications of polymeric microspheres prepared by the phase separation method were also presented.Furthermore,the advantages and shortcomings of the phase separation method had been analyzed in comparison to other common methods for the production of microspheres.Finally,the research and development trend of the phase separation method was proposed.

关 键 词：聚合物微球 相分离 机理 制备 应用 

分 类 号：TQ316.3[化学工程—高聚物工业]