阻塞性睡眠呼吸暂停低通气综合征患者的认知损害相关脑灰质影像学改变的研究进展  

Research Progress of Gray Matter Changes Associated with Cognitive Impairment in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

作　　者：黄雅楠 莫雨婷 徐运[1] HUANG Ya-nan;MO Yu-ting;XU Yun(Department of Neurology,Nanjing Drum Tower Hospital Clinical College of Jiangsu University,Nanjing 210008,China;Department of Neurology,Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University,Nanjing 210008,China)

机构地区：[1]江苏大学鼓楼临床医学院神经内科,南京210008 [2]南京医科大学鼓楼临床医学院神经内科,南京210008

出　　处：《中国临床神经科学》2023年第5期600-604,F0003,共6页Chinese Journal of Clinical Neurosciences

摘　　要：阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的睡眠片段化和间歇性低氧血症可导致患者的认知损害。目前,OSAHS引起认知损害的神经影像机制尚不明确。文中从脑灰质的角度,对OSAHS认知损伤相关的神经影像研究进行综述,以期为进一步探索OSAHS认知损害的神经影像标志物提供参考,为临床早期诊断、早期干预、改善患者预后提供支持。Obstructive sleep apnea hypopnea syndrome(OSAHS)is a serious breathing disorder,leading to intermittent oxygen desaturation and sleep fragmentation.Cognitive impairment is an important symptom of OSAHS,which has greatly affected the quality of life and long-term prognosis of patients.The neuroimaging mechanism of OSAHS-related cognitive impairment is unclear.The neuroimaging mechanism of OSAHS-related cognitive impairment,focusing on the gray matter and aiming to provide reference for further exploration in the future were reviewed.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 神经影像 认知损害 灰质 

分 类 号：R56[医药卫生—呼吸系统]