南充市2008—2022年丙型肝炎流行特征及趋势分析  

Analysis of epidemic characteristics and trend of hepatitis C in Nanchong city from 2008 to 2022

作　　者：林雪倩 李嘉兴[1] 兰洪彬 吴鹏 张芹[2] 张强[1] LIN Xue-qian;LI Jia-xing;LAN Hong-bin;WU Peng;ZHANG Qin;ZHANG Qiang(West China School of Public Health,Sichuan University/West China Fourth Hospital,Sichuan University,Chengdu,Sichuan 610041,China;不详)

机构地区：[1]四川大学华西公共卫生学院/华西第四医院,四川成都610041 [2]南充市疾病预防控制中心,四川南充637001

出　　处：《现代预防医学》2023年第21期4009-4014,共6页Modern Preventive Medicine

摘　　要：目的 分析2008—2022年南充市丙肝病例资料,掌握疫情现状和流行趋势。方法 收集各年份丙肝报告病例及人口学资料,应用Excel 2019和Arc GIS 10.6软件对数据进行分析及可视化处理,采用Joinpoint 4.9.0.0软件对丙肝年报告病例数进行趋势分析。结果 2008—2022年南充市累积报告丙肝5 394例,死亡3例,年均报告发病率为5.81/10万,病死率为0.055%;丙肝病例以年均15.62%的速率呈增长趋势,无明显季节特征。顺庆区(1 205例,10.79/10万)、南部县(874例,6.41/10万)、高坪区(623例,7.02/10万)报告病例数及发病率均居全市前三位。病例男女比为1.20:1,主要集中在30~59岁人群(3 433例,63.64%);0~19岁组男女病例相当,20~39岁组女性病例多于男性,40~59岁组男女病例均呈现上升趋势(AAPC:29.01%vs. 21.88%),60岁及以上组男女病例均呈现上升趋势(AAPC:19.28%vs. 14.86%)。农民(2 724例,50.50%)、家务及待业人群(1 134例,21.02%)报告病例数最多,且构成比均呈上升趋势(APC:5.23%vs.3.02%)。结论 2008—2022年南充市丙肝报告病例数整体呈现上升趋势,但处于低流行水平,需针对重点地区、重点场所、重点人群实施综合干预措施。Objective To analyze the data of hepatitis C cases in Nanchong from 2008 to 2022 and to understand the epidemic situation and epidemic trend.Methods The reported cases and demographic data of hepatitis C in different years were collected,and the data were analyzed and visualized by Excel2019 and ArcGIS10.6 software.The trend of annual reported cases of hepatitis C was analyzed by Joinpoint4.9.0.0 software.Results A total of 5394 cases of hepatitis C and 3 deaths were reported in Nanchong from 2008 to 2022,with an average annual reported incidence of 5.81/100000 and a fatality rate of 0.055%.The number of hepatitis C cases increased at an average annual rate of 15.62%,with no obvious seasonal characteristics.The number and incidence of reported cases in Shunqing district(1205 cases,10.79/100000),Nanbu county(874 cases,6.41/100000)and Gaoping district(623 cases,7.02/100000)were among the top three in the city.The ratio of male to female among the cases was 1.20,and the main age group was 30 to 59 years old(3433 cases,63.64%).In the age group of 0 to 19 years,the number of male and female cases was comparable,and in the age group of 20 to 39 years,the number of female cases was higher than that of male cases.In the age group of 40 to 59 years,the number of male and female cases showed an upward trend(AAPC:29.01%vs.21.88%),and in the age group of 60 years and above,the number of male and female cases also showed an upward trend(AAPC:19.28%vs.14.86%).The most affected population groups were farmers(2724,50.50%)and housewives and unemployed individuals(1134,21.02%),and the composition ratios were all on the rise(APC:5.23%vs.3.02%).Conclusion Hepetitis C cases in Nanchong city are on the rise,though still at the low prevalence level.Comprehensive interventions targeting key areas,key places,and key populations are urgently needed to reduce the incidence of HCV infection.

关 键 词：丙型肝炎 南充市 流行趋势 Joinpoint 

分 类 号：R512.63[医药卫生—内科学]