2018—2021年COVID-19疫情前后国内18家血液中心红细胞成分血供应情况分析  

Analysis of red blood cells supply before and after the outbreak of COVID-19 from 2018 to 2021 in 18 domestic blood centers

作　　者：赵冬雁[1] 马宏伟[2] 汤丁洁[3] 冯晓荣 田浩[5] 罗孟卓 吴南 林妍[8] 杜霞[9] 傅奇[10] 黄均磊 卢长春[12] 曹晓莉[13] 杨毅 王林[15] 李莹[16] 戚海[17] 王东泰 邱艳[1] ZHAO Dongyan;MA Hongwei;TANG Dingjie;FENG Xiaorong;TIAN Hao;LUO Mengzhuo;WU Nan;LIN Yan;DU Xia;FU Qi;HUANG Junlei;LU Changchun;CAO Xiaoli;YANG Yi;WANG Lin;LI Ying;QI Hai;WANG Dongtai;QIU Yan(Beijing Red Cross Blood Center,Beijing 100088,China;Henan Red Cross Blood Center;Jiangsu Province Blood Center;Gansu Red Cross Blood Center;Chengdu Blood Center;Changsha Blood Center;Inner Mongolia Blood Center;Liaoning Province Blood Center;Yunnan Kunming Blood Center;Chongqing Blood Center;Shandong Blood Center;Harbin Blood Center;Shaanxi Blood Center;Ningxia Blood Center;Hainan Province Blood Center;Jiangxi Province Blood Center;Hebei Blood Center;Taiyuan Blood Center)

机构地区：[1]北京市红十字血液中心,北京100088 [2]河南省红十字血液中心 [3]江苏省血液中心 [4]甘肃省红十字血液中心 [5]成都市血液中心 [6]长沙血液中心 [7]内蒙古自治区血液中心 [8]辽宁省血液中心 [9]云南昆明血液中心 [10]重庆市血液中心 [11]山东省血液中心 [12]黑龙江省血液中心 [13]陕西省血液中心 [14]宁夏回族自治区血液中心 [15]海南省血液中心 [16]江西省血液中心 [17]河北省血液中心 [18]太原市血液中心

出　　处：《中国输血杂志》2023年第10期892-898,共7页Chinese Journal of Blood Transfusion

基　　金：河南省医学科技攻关计划项目(RKX202002017)。

摘　　要：目的对2018—2021年新型冠状病毒感染(COVID-19)前后国内18家血液中心红细胞成分血供应相关数据进行比较分析。方法采用回顾性研究方法,收集2018—2021年国内18家血液中心红细胞成分血供应相关的8个数据,包括合格红细胞成分血入库总量(简称入库总量)、红细胞成分血发放总量(简称发放总量)、每千人口红细胞成分血发放量(简称每千人口发放量)、每千人口400 mL全血制备的红细胞成分血发放量[简称每千人口发放量(400 mL)]、红细胞成分血日均发放量(简称日均发放量)、红细胞成分血日均库存量(简称日均库存量)、发放时红细胞成分血平均天数(简称红细胞天数)、红细胞成分血过期量(简称过期量)。根据COVID-19发生时间,2018、2019年数据为疫情爆发前组,2020、2021年数据为疫情爆发后组。结果2018—2021年18家血液中心红细胞成分血供应相关数据,疫情前组与疫情后组比较,每千人口发放量(中位数14.68 U>13.92 U)、每千人口发放量(400 mL)(中位数10.16 U>9.21 U)减少,差异有统计学意义(P<0.05);2019、2020年数据比较,发放总量(中位数117770.38 U>99084.08 U)、每千人口发放量(中位数15.04 U>12.19 U)、每千人口发放量(400 mL)(中位数10.11 U>8.94 U)、日均发放量(中位数322.66 U>270.73 U)减少,红细胞天数(中位数10.50 d<11.45 d)增加,差异有统计学意义(P<0.05);2020、2021年数据比较,入库总量(中位数101920.25 U<120328.63 U)、发放总量(中位数99084.08 U<118428.62 U)、每千人口发放量(中位数12.19 U<15.00 U)、每千人口发放量(400 mL)(中位数8.94 U<9.46 U)、日均发放量(中位数270.73 U>324.46 U)、日均库存量(中位数3222.00 U<4328.00 U)增加,过期量(中位数1.50 U>0.00 U)减少,差异有统计学意义(P<0.05)。方差分析结果显示,不同采供血机构的红细胞成分血供应相关数据(除过期量外)存在显著差异(P<0.05);日均库存量与日均发放量之比疫情爆发后�Objective To compare the supply data of red blood cells(RBCs)from 18 blood centers in China before and after the outbreak of COVID-19 during 2018 to 2021.Methods Eight indicators related to RBCs supply from 18 blood centers in China during 2018-2021 were collected retrospectively,including the storage of total amount of qualified RBCs(referred to as the total amount of storage),the distribution of total amount of RBCs(referred to as the total amount of distribution),the distribution amount of RBCs per 1000 population(referred to as the amount of distribution per 1000 population),the distribution amount of RBCs from 400 mL original blood per 1000 population[referred to as the amount of distribution per 1000 population(400 mL)],the average daily distribution amount of RBCs(referred to as the average daily distribution amount),the average daily storage amount of RBCs(referred to as the average daily storage amount),the average storage days of RBCs when distribute(referred to as the RBC storage days),and the expired amount of RBCs(referred to as the expired amount).Based on the outbreak time of COVID-19,the data of 2018 and 2019 were the pre-pandemic group,and the data of 2020 and 2021 were the post-pandemic group.Results Data on RBCs supply in 18 blood centers from 2018 to 2021(comparison of the pre-pandemic group and the post-pandemic group):the amount of distribution per 1000 population(median 14.68 U>13.92 U)decreased,the amount of distribution per 1000 population(400 mL)(median 10.16 U>9.21 U)decreased,and the difference was statistically significant(P<0.05);data comparison between 2019 and 2020:the total amount of distribution(median 117770.38 U>99084.08 U)decreased,the amount of distribution per 1000 population(median 15.04 U>12.19 U)decreased,the amount of distribution per 1000 population(400 mL)(median 10.11 U>8.94 U),the average daily distribution amount(322.66 U>270.73 U)decreased and RBC storage days(median 10.50 d<11.45 d)increased,the difference has statistical significance(P<0.05);data comparison betwe

关 键 词：新型冠状病毒 红细胞成分血 血液供应 血液安全 

分 类 号：R331.141[医药卫生—人体生理学]