高效邻苯二甲酸新戊二醇聚酯毛细管柱的制备及应用  

Preparation and application of high efficiency neopentyl glycol phthalate polyester capillary column

作　　者：石昆 秦金平 徐国庆 魏昊东 SHI Kun;QIN Jinping;XU Guoqing;WEI Haodong(College of Chemical Engineering,Nanjing Technology University,Nanjing 211816,China)

机构地区：[1]南京工业大学化工学院,南京211816

出　　处：《分析试验室》2023年第10期1380-1385,共6页Chinese Journal of Analysis Laboratory

摘　　要：用邻苯二甲酸和新戊二醇合成了邻苯二甲酸新戊二醇聚酯,并对其进行了核磁和红外光谱表征,确定了该物质的微观结构。使用超细SiO_(2)载体水溶液对毛细管柱内壁进行表面粗糙化处理,以邻苯二甲酸新戊二醇聚酯为固定相,配制5 mg/mL的固定液,用静态法涂渍了毛细管色谱柱,制备了0.25 mm×30 m×0.32μm邻苯二甲酸新戊二醇聚酯毛细管柱。以甲酚、二甲酚异构体的分离能力评价其分离性能。结果表明,邻苯二甲酸新戊二醇聚酯毛细管柱对甲酚、二甲酚异构体具有良好的分离能力,每米理论塔板数在3000左右,其最高使用温度为250℃。建立了用于检测高纯度间甲酚、对甲酚的方法。Neopentyl glycol phthalate polyester was synthesized from phthalic acid and neopentyl glycol,and its microstructure was characterized by nuclear magnetic resonance(NMR) and infrared radiation(IR).The inner wall of capillary column was roughened by using ultrafine SiO_(2) carrier aqueous solution.The capillary chromatography column(0.25 mm×30 m×0.32 μm) was successfully prepared by static method,using neopentyl glycol phthalate polyester(5 mg/mL) as stationary phase.The separation performance of cresol and xylenol isomers was evaluated.The results showed that the capillary column of neopentyl phthalate had good separation ability for cresol and xylcresol isomers,the number of theoretical plates per meter was around 3000 and the highest operating temperature was 250 ℃.A method for the analysis of m-cresol and p-cresol with high purity was established.

关 键 词：邻苯二甲酸新戊二醇聚酯 毛细管色谱 甲酚异构体 二甲酚异构体 

分 类 号：O657.71[理学—分析化学]