少腹逐瘀汤用于孕中期药物引产效果及对子宫复旧影响  

nfluence of Shaofu zhuyu decoction used for medical termination of the second trimester pregnancy of women and its influence on the uterine recovery of these women

作　　者：赵红霞 王惠 吴平易 杨晓红[3] ZHAO Hongxia;WANG Hui;WU Pingyi;YANG Xiaohong(Postgraduate Training Base,Xiaogan Central Hospital,Jinzhou Medical University,Xiaogan,Hubei Province,432100;Xiantao City Maternal and Child Health Care Hospital,Hubei Province;Xiaogan Central Hospital,Hubei Province)

机构地区：[1]锦州医科大学孝感市中心医院研究生培养基地,432100 [2]湖北省仙桃市妇幼保健院 [3]湖北省孝感市中心医院

出　　处：《中国计划生育学杂志》2023年第11期2554-2558,共5页Chinese Journal of Family Planning

摘　　要：目的:分析少腹逐瘀汤联合米非司酮加米索前列醇对中期妊娠引产的疗效及子宫复旧的影响。方法:选取2021年3月-2022年3月本院拟中期妊娠引产者80例,依照随机数字表法分为对照组和观察组各40例,两组均给予米非司酮+米索前列醇,观察组给予少腹逐瘀汤,对比两组引产效果、炎症因子、月经复潮时间、子宫内膜厚度、引产结局、并发症情况。结果:观察组宫缩发动时间(23.57±3.86 h)、胚胎娩出时间(4.76±0.96 d)及阴道流血停止时间(5.95±0.81 d)均短于对照组(30.30±4.03 h、5.56±1.19 d、9.20±1.25 d),引产后1 d、3 d血C反应蛋白、白细胞计数、中性粒细胞比值水平均低于对照组,引产后7d及月经复潮后7d子宫内膜厚度(7.24±1.04mm、8.34±2.15mm)高于对照组(6.02±0.87mm、6.55±1.59mm),月经复潮时间(36.90±3.03d)短于对照组(44.65±3.27d),并发症发生率(7.5%)低于对照组(25.0%)(均P<0.05),完全引产率(72.5%)与对照组(50.0%)无差异(P>0.05)。结论:采用少腹逐瘀汤联合米非司酮加米索前列醇中期引产可缩短蜕膜脱落时间,流产后恢复较快,利于子宫内膜修复,且可缓解机体炎性反应。Objective:To analyze the efficacy of Shaofu zhuyu decoction combined with mifepristone and misoprostol for mid-term labor induction of women,and to study its influence on the uterine recovery of the women.Methods:A total of 80 women who wanted mid-term labor induction were selected and were divided into two groups(40 cases in each group)according to the random number table method from March 2021 to March 2022.The women in the control group were given mifepristone and misoprostol for mid-term labor induction and the women in the study group were given mifepristone and misoprostol combined with Shaofu zhuyu decoction for mid-term labor induction.The effect of labor induction,the inflammatory factors levels,the menstrual recovery time,the endometrial thickness,the labor induction outcomes,and the complications situation of the women were compared between the two groups.Results:The time of uterine contraction start(23.57±3.86 h),the embryo delivery time(4.76±0.96 d),and the vaginal bleeding stop time(5.95±0.81 d)of the women in the study group were significantly shorter than those(30.30±4.03 h,5.56±1.19 d,and 9.20±1.25 d)of the women in the control group.The levels of blood C-reactive protein,the white blood cell count,and the neutrophil ratio of the women in the study group in the 1st and the 3rd day after induction of labor were significantly lower than those of the women in the control group.The endometrial thickness of the women in the study group in the 7th day after induction of labor(7.24±1.04mm)and in the 7th day(8.34±2.15mm)after the recovery of menstruation were significantly higher than those(6.02±0.87mm and 6.55±1.59mm)of the women in the control group.The recovery time of menstruation(36.90±3.03d)of the women in the study group was significantly shorter than that(44.65±3.27d)of the women in the control group.The incidence of complications(7.5%)of the women in the control group was significantly lower than that(25.0%)of the women in the control group,and the complication rate(72.5%)of the wome

关 键 词：药物中期引产 米非司酮 米索前列醇 少腹逐瘀汤 引产效果 子宫恢复 月经复潮 炎性反应 

分 类 号：R271.9[医药卫生—中西医结合]