响应面法优化荔枝草中总黄酮的提取工艺  

Optimization of the Extraction Process of Total Flavonoids from Salviaplebeia R. Br. by Response Surface Methodology

作　　者：兰艳素[1] 潘乐[1] 黄义橙 周蝶 Lan Yansu;Pan Le;Huang Yicheng;Zhou Die(School of Chemistry and Chemical Engineering,Huangshan University,Huangshan 245041,China)

机构地区：[1]黄山学院化学化工学院,安徽黄山245041

出　　处：《黄山学院学报》2023年第5期37-42,共6页Journal of Huangshan University

基　　金：安徽省高校自然科学研究项目(KJHS2020B06);黄山学院人才启动项目(2020xkjq020)。

摘　　要：采用微波法辅助提取荔枝草中的总黄酮成分,根据单因素试验结果,通过建立Central Composite Design方案并进行拟合分析,得到4个自变量微波提取时间、微波功率、乙醇体积分数和液料比对总黄酮提取率的影响模型,确定最佳提取工艺条件为:微波提取时间6.5min,微波功率623.7W,液料比30.3:1(mL/g),乙醇体积分数为51%,总黄酮提取率为2.093%。所得模型具有较好预测性,可为荔枝草资源的开发提供参考。The total flavonoids in Salvia plebeia R.Br.were extracted by the microwave-assisted methodology.According to the single factor results,the central composite design scheme was established and the model of four independent variables’(microwave extraction time,microwave power,ethanol concentration and liquid-solid)influence on the extraction rate of total flavonoids was obtained by fitting analysis.The optimal extraction process conditions were determined as follows:microwave extraction time was 6.5 min,microwave power was 623.7 W,liquid-solid ratio was 30.3:1(mL/g),ethanol concentration was 51%,and the extraction rate of total flavonoids was 2.093%.The model has shown good predictability and can provide reference for the development of the Salvia plebeia R.Br.resources.

关 键 词：荔枝草 响应面法 总黄酮 微波辅助提取 

分 类 号：R284.2[医药卫生—中药学]