镧系Eu^(3+)/PMMA聚合物杂化探针的制备及其对唾液酸的传感检测应用  

Preparation and Sensing Detection Application of Lanthanide Eu^(3+)/PMMA Polymer Hybrid Probe

作　　者：闵华[1] 刘丽[2] 夏继绩 徐陈 唐思祎 李颖[2] MIN Hua;LIU Li;XIA Jiji;XU Chen;TANG Siyi;LI Ying(Technology Transfer Center,Institute of Science and Technology Development,University of Shanghai for Science and Technology,Shanghai 200093,China;School of Materials&Chemistry,University of Shanghai for Science and Technology,Shanghai 200093,China)

机构地区：[1]上海理工大学科技发展研究院技术转移中心,上海200093 [2]上海理工大学材料与化学学院,上海200093

出　　处：《发光学报》2023年第11期2076-2080,共5页Chinese Journal of Luminescence

基　　金：国家自然科学基金(21101107,51173107);污染控制与资源化国家重点实验室基金项目(PCRRF19017)。

摘　　要：设计合成了一种Eu^(3+)离子功能化的聚合物基稀土杂化探针。利用苯甲酰三氟丙酮(BFA)与镧系Eu^(3+)进行配位反应得到配合物Eu(BFA)_(3)后再进一步与MMA单体进行聚合制备得到聚合物杂化探针分子Eu‐(BFA)_(3)@PMMA,对Eu(BFA)_(3)@PMMA的结构和荧光性能进行了详细的探究,并且将其用于肿瘤标志物唾液酸(SA)的传感检测应用。研究结果表明,SA能对Eu(BFA)_(3)@PMMA的荧光产生明显的猝灭效果。此外,在最佳激发波长为325 nm时进行荧光性能对比实验发现Eu(BFA)_(3)@PMMA对SA具有较强的选择性和抗干扰能力,且检出限较低。In this paper,a polymer-based rare earth hybrid probe functionalized by Eu^(3+)was designed and synthe⁃sized.The coordination reaction between benzoyl trifluoroacetone(BFA)and lanthanide Eu^(3+)was used to obtain the complex Eu(BFA)_(3),which was further prepared by polymerization with MMA monomer to obtain polymer hybrid probe Eu(BFA)[e-mail] structure and fluorescence properties of Eu(BFA)_(3)@PMMA were investigated in de⁃tail.It is also used in the sensor detection of tumor marker sialic acid(SA).The results showed that SA can produce a significant quenching effect on the fluorescence of Eu(BFA)_(3)@PMMA.In addition,fluorescence properties con⁃trast experiments at excitation wavelength of 325 nm showed that Eu(BFA)_(3)@PMMA had strong selectivity and antiinterference ability for SA,and the detection limit was low.

关 键 词：镧系配合物 杂化探针 唾液酸 荧光传感 

分 类 号：O482.31[理学—固体物理]