妊娠期高血压疾病的产科临床治疗效果分析  

Analysis of Obstetric Clinical Treatment Effects on Hypertensive Disorders during Pregnancy

作　　者：黄小娟[1] HUANG Xiaojuan(Zhangzhou Traditional Chinese Medicine Hospital,Zhangzhou 363000,China)

机构地区：[1]福建省漳州市中医院,福建漳州363000

出　　处：《中国医药指南》2023年第33期101-103,共3页Guide of China Medicine

摘　　要：目的探讨并分析妊娠期高血压疾病的产科临床治疗效果。方法选取我院2021年9月至2023年8月期间收治的188例妊娠期高血压疾病患者展开研究,遵循随机数字表法分组原则,将其分为参照组(硫酸镁治疗)与试验组(硫酸镁联合硝苯地平治疗),每组94例。观察两组血压水平、血清学指标、治疗疗效、不良反应以及妊娠结局。结果治疗前,两组患者收缩压、舒张压水平并无显著差异,P>0.05;治疗后,两组患者收缩压、舒张压水平均有所降低,而且试验组患者收缩压、舒张压水平均低于参照组,P<0.05。试验组CRP、Hcy、MDA、TAC、SOD、GSH-Px、治疗有效率、不良反应发生率均优于参照组,P<0.05。两组在新生儿病死率上差异无统计学意义,P>0.05;但试验组剖宫产率21.28%、产后出血率4.26%、早产率2.13%、新生儿窒息率1.06%,均低于参照组的43.62%、12.77%、15.96%、11.70%,P<0.05。结论硫酸镁联合硝苯地平治疗妊娠期高血压疾病的临床效果显著,可有效地控制患者血压水平,改善血清学指标,提高临床治疗有效性,并降低不良反应,改善妊娠结局。Objective To explore and analyze the clinical treatment effects of obstetrics for gestational hypertension.Methods A study was conducted on 188 patients with gestational hypertension admitted to our hospital from September 2021 to August 2023.Following the principle of random number table grouping,they were divided into a reference group(treated with magnesium sulfate)and an experimental group(treated with magnesium sulfate combined with nifedipine),with 94 patients in each group.Observe blood pressure levels,serological indicators,treatment efficacy,adverse reactions,and pregnancy outcomes in both groups.Results Before treatment,there was no significant difference in systolic and diastolic blood pressure levels between the two groups of patients,P>0.05;After treatment,the average systolic and diastolic blood pressure in both groups of patients decreased,and the average systolic and diastolic blood pressure in the experimental group was significantly lower than that in the reference group,P<0.05.The CRP,Hcy,MDA,TAC,SOD,GSH-Px levels,effective rate,incidence of adverse reactions in the experimental group were better than the reference group,P<0.05.There was no statistically significant difference in neonatal mortality between the two groups,P>0.05;However,the experimental group had a cesarean section rate of 21.28%,postpartum hemorrhage rate of 4.26%,preterm birth rate of 2.13%,and neonatal asphyxia rate of 1.06%,all lower than the reference group's 43.62%,12.77%,15.96%,and 11.70%,P<0.05.Conclusions The clinical effect of magnesium sulfate combined with nifedipine in the treatment of gestational hypertension is significant.It can effectively control patient blood pressure levels,improve serological indicators,enhance clinical treatment effectiveness,reduce adverse reactions,and improve pregnancy outcomes.

关 键 词：妊娠期高血压疾病 硫酸镁 硝苯地平 血压 血清学指标 

分 类 号：R714.246[医药卫生—妇产科学]