探讨纤维支气管镜治疗急危重症合并严重肺部感染的疗效  

Discussion on efficacy of fiberoptic bronchoscopy in the treatment of acute and critical patients with severe pulmonary infection

作　　者：穆少宁 吴春燕 MU Shao-ning;WU Chun-yan(Liaocheng Hospital of Traditional Chinese Medicine,Liaocheng 252000,China)

机构地区：[1]聊城市中医医院,252000

出　　处：《中国实用医药》2023年第21期52-55,共4页China Practical Medicine

摘　　要：目的探讨急危重症合并严重肺部感染患者应用纤维支气管镜治疗的临床效果。方法60例急危重症合并严重肺部感染患者,随机分为对照组和观察组,每组30例。对照组应用常规治疗,观察组在常规基础治疗上应用纤维支气管镜治疗。比较两组患者各项生命指征[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))、动脉血氧饱和度(SaO_(2))]变化及C反应蛋白(CRP)水平、临床症状改善时间、治疗效果。结果观察组PaO2(95.36±9.56)mm Hg(1 mm Hg=0.133 kPa)、SaO_(2)(97.63±3.69)%均高于对照组的(88.71±9.36)mm Hg、(92.41±2.23)%,PaCO_(2)(42.28±3.52)mm Hg低于对照组的(46.09±3.39)mm Hg,差异具有统计学意义(P<0.05)。观察组退热时间(4.63±1.20)d、痰液减少时间(5.65±1.27)d、痰菌培养转阴时间(5.42±1.23)d、肺部啰音消失时间(5.63±0.39)d均短于对照组的(7.56±2.14)、(8.44±1.52)、(7.06±2.78)、(8.36±1.12)d,差异具有统计学意义(P<0.05)。观察组治疗总有效率96.67%高于对照组的80.00%,差异具有统计学意义(P<0.05)。观察组血清CRP水平为(23.03±5.82)mg/L,低于对照组的(36.36±5.83)mg/L,差异具有统计学意义(P<0.05)。结论急危重症合并严重肺部感染患者应用纤维支气管镜治疗更有助于生命指征的恢复,缩短患者症状恢复时间,具有较为满意的临床效果。Objective To discuss the clinical effect of fiberoptic bronchoscopy in the treatment of acute and critical patients with severe pulmonary infection.Methods A total of 60 cases of acute and critical patients with severe pulmonary infection were randomly divided into control group and observation group,with 30 cases in each group.The control group received conventional treatment,and the observation group received fiberoptic bronchoscopy on the basis of conventional treatment.Both groups were compared in terms of changes of vital indicators[arterial partial pressure of oxygen(PaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2)),arterial oxygen saturation(SaO_(2))],C-reactive protein(CRP)level,clinical symptom improvement time,and therapeutic effect.Results PaO2 of(95.36±9.56)mm Hg(1mm Hg=0.133 kPa)and SaO2 of(97.63±3.69)%in the observation group were higher than those of(88.71±9.36)mm Hg and(92.41±2.23)%in the control group;PaCO2 of(42.28±3.52)mm Hg in the observation group was lower than that of(46.09±3.39)mm Hg in the control group;the differences were statistically significant(P<0.05).In the observation group,the time of fever reduction was(4.63±1.20)d,the time of sputum reduction was(5.65±1.27)d,the time of sputum culture negative convertion was(5.42±1.23)d and the time of lung rale disappearing was(5.63±0.39)d,which were all shorter than those of(7.56±2.14),(8.44±1.52),(7.06±2.78),and(8.36±1.12)d in the control group,and the differences were statistically significant(P<0.05).The total effective rate of the observation group was 96.67%,which was higher than that of 80.00%of the control group,and the difference was statistically significant(P<0.05).The serum CRP level of(23.03±5.82)mg/L in the observation group was lower than that of(36.36±5.83)mg/L in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of fiberoptic bronchoscopy is more helpful to the recovery of vital signs of acute and critical patients with severe pulmonary infection,

关 键 词：纤维支气管镜 急危重症 严重肺部感染 

分 类 号：R563.1[医药卫生—呼吸系统] R459.7[医药卫生—内科学]