某院结核病科抗菌药物的合理用药点评分析  

Review and Analysis of Rational Use of Antibacterial Drugs in Tuberculosis Department of a Hospital

作　　者：欧阳淑萍 欧阳涵怡 付志刚 OUYANG Shu-ping;OUYANG Han-yi;FU Zhi-gang(Disease Control and Prevention Center of Anfu County,Anfu Jiangxi 343200,China;The Third Clinical Medical College of Nanchang University,Nanchang 330006 China;Anfu County People's Hospital,Anfu Jiangxi 343200,China)

机构地区：[1]安福县疾病预防控制中心,江西安福343200 [2]南昌大学第三临床医学院,南昌330006 [3]安福县人民医院,江西安福343200

出　　处：《抗感染药学》2023年第7期701-704,共4页Anti-infection Pharmacy

摘　　要：目的:点评和分析医院结核病科抗菌药物的合理用药情况,为临床的抗菌药物合理使用提供参考。方法:选取2021年1月—2022年12月医院结核病科的3694张(条)抗菌药物处方(或医嘱)作为研究资料,根据相关指南、专家共识、药品说明书等权威资料对抗菌药物的使用情况进行点评,分析抗菌药物不合理使用的特点。结果:点评发现,3694张抗菌药物处方(或医嘱)中存在不合理处方(或医嘱)311张(条),不合理发生率为8.42%;根据原因类型不同,311张不合理处方(或医嘱)可分为不规范处方(或医嘱)(232张,主要表现为诊断书写不规范)和不适宜处方(或医嘱)(79张,主要表现为药物用法用量不适宜);311张不合理处方(或医嘱)涉及的抗菌药物品种主要有左氧氟沙星(86张,占27.65%)、阿莫西林-克拉维酸钾(56张,占18.01%)和莫西沙星(52张,占16.72%);60张药物用法用量不适宜处方(或医嘱)涉及的药物主要为莫西沙星(29张,占48.33%)。结论:医院结核病科抗菌药物的使用整体较为合理,但个别品种存在较多的不合理情况,临床应该加强对相关药物的培训和管理,从而促进临床抗菌药物的合理使用。Objective:To review and analyze the rational use of antibacterial drugs in Tuberculosis Department of the hospital,so as to provide reference for the rational use of antibacterial drugs in clinical practices.Methods:3694 prescriptions(or doctor's advices)for antibacterial drugs in Tuberculosis Department of the hospital from January 2021 to December 2022 were selected as the research data,and the use of antibacterial drugs was reviewed based on authoritative information such as related guidelines,experts'consensus and drug instructions,so as to analyze the characteristics of irrational use of antibacterial drugs.Results:According to the review,311 prescriptions(or doctor's advices)out of 3694 prescriptions(or doctor's advices)for antibacterial drugswere irrational,with an irrationality occurrence rate of 8.42%.Based on the types of reasons,311 irrational prescriptions(or doctor's advices)can be categorized into irregular prescriptions(or doctor's advices)(232,mainly for irregular diagnosis writing)and inappropriate prescriptions(or doctor's advices)(79,mainly for inappropriate usage and dosage of drugs).Among 311 irrational prescriptions(or doctor's advices),the main types of antibacterial drugs involved were levofloxacin(86,27.65%),amoxicillin-clavulanate potassium(56,18.01%)and moxifloxacin(52,16.72%).60 prescriptions(or doctor's advices)with inappropriate usage and dosage of drugs weremainly for moxifloxacin(29,48.33%).Conclusion:The use of antibacterial drugs in Tuberculosis Department of the hospital is rational on the whole,but there are relatively more irrational situations in individual varieties.It is necessary to strengthen the clinical training and management of related drugs,so as to promote the clinical rational use of antibacterial drugs.

关 键 词：抗菌药物 合理用药点评 结核病科 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]