腹膜透析相关动物模型的研究进展  

Research progresses in peritoneal dialysis related animal models

作　　者：方吕贵[1] 饶向荣[2] FANG Lv-gui;RAO Xiang-rong(Department of Nephrology,South District of Guang-An-Men Hospital,China Academy of Chinese Medical Sciences,Beijing 102600,China;Department of Nephrology,Guang-An-Men Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)

机构地区：[1]中国中医科学院广安门医院南区肾病科,北京102600 [2]中国中医科学院广安门医院肾病科,北京100053

出　　处：《中国血液净化》2023年第11期850-852,共3页Chinese Journal of Blood Purification

基　　金：国家自然科学基金(82204899);中国中医科学院优秀青年科技人才培养专项(ZZ16-YQ-015)。

摘　　要：腹膜透析动物模型为人类改善腹膜透析治疗提供了重要的参考和依据,虽然到人类临床应用之前,仍需进行更多的研究和验证。目前研究者们已经使用小鼠、大鼠、兔子、猪等动物建立了腹膜透析动物模型。从新型透析液的研发,到腹膜炎、腹膜纤维化等并发症的治疗和机制研究,腹膜透析动物模型都发挥了重要的价值。Peritoneal dialysis(PD)related animal models provide important references for improving PD treatment in humans,despite the fact that animal results have to be further studied before they can be used clinically.Currently,PD related models have been established in mice,rats,rabbits,pigs and other animals.These animal models offer valuable information about the mechanisms of PD complications such as peritonitis and peritoneal fibrosis,and also about the development of new dialysates.

关 键 词：腹膜透析 动物模型 

分 类 号：R459.5[医药卫生—治疗学]