焦虑情绪与青年人颈动脉弹性的相关性研究  

Correlation between anxiety and carotid artery elasticity in young adults

作　　者：王秋月 王湘竹 何丽丽 王岳青 杨友财 王尔玉 单贝贝 李娜[1] 谢颖桢[1] WANG Qiuyue;WANG Xiangzhu;HE Lili;WANG Yueqing;YANG Youcai;WANG Eryu;SHAN Beibei;LI Na;XIE Yingzhen(Department of EncephalopathyⅡ,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)

机构地区：[1]北京中医药大学东直门医院脑病二科,北京市100700 [2]北京中医药大学第三附属医院超声科

出　　处：《临床超声医学杂志》2023年第11期900-904,共5页Journal of Clinical Ultrasound in Medicine

基　　金：北京市科技计划课题(Z191100006619065)。

摘　　要：目的 探讨焦虑情绪与青年人颈动脉弹性的相关性。方法 选取我院脑病科门诊因失眠或焦虑就诊的78例青年人,根据汉密尔顿焦虑量表(HAMA)评分将其分为焦虑组31例(HAMA评分≥14分)和不焦虑组47例(HAMA评分<7分),比较两组受试者双侧颈动脉内中膜厚度(IMT)、扩张系数(DC)、膨胀系数(CC)、僵硬度(α、β)、脉搏波传导速度(PWV)的差异;分析HAMA评分与上述颈动脉弹性参数的相关性。结果 与不焦虑组比较,焦虑组右侧颈动脉IMT,以及双侧α、β、PWV均增大,右侧颈动脉DC及左侧颈动脉DC、CC均减小,差异均有统计学意义(均P<0.05)。双侧颈动脉DC、CC均与HAMA评分呈负相关(均P<0.05),双侧颈动脉α、β、PWV均与HAMA评分呈正相关(均P<0.05);在控制年龄、性别、身高、体质量、体质量指数、血压等相关因素后,左侧颈动脉CC仍与HAMA评分呈负相关(P<0.05),左侧颈动脉α、β、PWV仍与HAMA评分均呈正相关(均P<0.05)。结论 情绪焦虑的青年人睡眠质量更差、压力水平更高;焦虑情绪与青年人颈动脉IMT增厚、弹性降低相关,焦虑情绪越明显,颈动脉弹性越差。Objective To explore the correlation between anxiety and carotid artery elasticity in young adults.Methods A total of 78 young adults with insomnia or anxiety at the neurology outpatient department of our hospital were selected.According to the Hamilton Anxiety Scale(HAMA)scores,they were divided into anxiety group(31 cases with HAMA score≥14)and non-anxiety(47 cases with HAMA score<7).The differences in bilateral carotid intima-media thickness(IMT),dilation coefficient(DC),dilation coefficient(CC),stiffness(αandβ),and pulse wave velocity(PWV)were compared between the two groups.The correlation between HAMA scores and the carotidartery elasticity parameters were analyzed.Results Compared with the non-anxiety group,the right carotid IMT,bilateral carotidα,β,PWV increased,and the right carotid DC and left carotid DC,CC decrease,there were statistically significant differences(all P<0.05).Bilateral carotid artery DC and CC were negatively correlated with HAMA scores(all P<0.05),and bilateral carotid arteryα,β,and PWV were positively correlated with HAMA scores(all P<0.05).After controlling for factors such as age,gender,height,body weight,body mass index,blood pressure,etc.,left carotid artery CC was still negatively correlated with HAMA scores(P<0.05),and left carotid arteryα,β,and PWV were still positively correlated with HAMA scores(all P<0.05).Conclusion Young adults with anxiety experience poorer sleep quality and higher stress levels.Anxiety is correlated with increased IMT and decreased elasticity of the carotid artery in young adults.The more pronounced the anxiety,the poorer the carotid artery elasticity.

关 键 词：超声检查 颈动脉弹性 焦虑 

分 类 号：R445.1[医药卫生—影像医学与核医学] R749.72[医药卫生—诊断学]