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作 者:彭彬[1] 张欣瑜[1] Peng Bin;Zhang Xinyu(Jiangmen Xinhui District People's Hospital,Jiangmen 529100,Guangdong Province,China)
出 处:《中外医药研究》2023年第21期48-50,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
摘 要:目的:探讨介入栓塞治疗颅内微小动脉瘤的临床疗效。方法:选取2021年1月—2023年1月江门市新会区人民医院收治的颅内微小动脉瘤77例作为研究对象,根据治疗方法差异将其分为介入组(n=34,采取介入栓塞治疗)与夹闭组(n=33,采取开颅夹闭治疗),比较两组患者临床疗效、神经功能缺损情况、生活能力、术中及术后不良情况及远期疗效。结果:介入组患者有效率高于夹闭组,差异有统计学意义(P=0.041);介入组患者美国国立卫生研究院卒中量表评分低于夹闭组,日常生活活动能力评分高于夹闭组,差异有统计学意义(P<0.05);两组患者不良情况发生率比较,差异无统计学意义(P>0.05);两组患者改良Rankin量表评分比较,差异无统计学意义(P>0.05);两组患者术后远期临床疗效比较,差异无统计学意义(P>0.05)。结论:介入栓塞治疗颅内微小动脉瘤近期临床效果较好,远期疗效与开颅夹闭术相当,安全性较高,治疗后患者神经功能缺损情况及生活能力得到显著改善。Objective:To explore the clinical efficacy of interventional embolization for intracranial microaneurysms.Methods:Seventy-seven cases of intracranial microaneurysms admitted to Jiangmen Xinhui District People's Hospital from January 2021 to January 2023 were selected as the study subjects.According to the difference of treatment methods,they were divided into intervention group(n=34,taking intervention embolization treatment)and clamping group(n=33,taking craniotomy clamping treatment).The clinical efficacy,neurological deficit,living ability,intraoperative and postoperative malpractice and long-term efficacy were compared between the two groups.Results:The effective rate of patients in the intervention group was higher than that of the clamping group,and the difference was statistically significant(P=0.041);The National Institutes of Health Stroke Scale score of patients in the intervention group was lower than that of the clamping group,and the score of ability to perform activities of daily living was higher than that of the clamping group,and the difference was statistically significant(P<0.05);Comparison of the incidence of adverse conditions between the two groups of patients,the difference was not statistically significant(P>0.05);Comparison of the modified Rankin scale scores of patients in the two groups,the difference was not statistically significant(P>0.05);Comparison of postoperative long-term clinical efficacy between the two groups of patients,the difference was not statistically significant(P>0.05).Conclusion:Interventional embolization treatment of intracranial microaneurysms has a better clinical effect in the near future,and the long-term efficacy is comparable to craniotomy,with higher safety,and the patients'neurological deficits and ability to live have been significantly improved after the treatment.
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