南京市梅山地区非肥胖人群动脉硬化的发生率及相关因素  

Incidence of arteriosclerosis and associated factors in non-obese population in Meishan district in Nanjing

作　　者：王阳春 仝瑞祥 何忠华 方琴 陈婷婷 刘军军 WANG Yangchun;TONG Ruixiang;HE Zhonghua;FANG Qin;CHEN Tingting;LIU Junjun(Department of Endocrinology,Nanjing Meishan Hospital,Nanjing,210039,China;Nanjing Medical University;Department of Psychiatry,Nanjing Meishan Hospital)

机构地区：[1]南京梅山医院内分泌科,南京210039 [2]南京医科大学 [3]南京梅山医院精神科

出　　处：《临床心血管病杂志》2023年第10期793-797,共5页Journal of Clinical Cardiology

基　　金：南京市医学科技发展基金项目(No:YKK20184、YKK21216、YKK22264)。

摘　　要：目的:探讨南京市梅山地区非肥胖人群动脉硬化(arteriosclerosis,AS)的发生率及相关危险因素。方法:收集2017年8月—2021年7月南京梅山医院体检中心招募的非肥胖人群861例,年龄24~84岁,平均(51.4±9.49)岁,其中男554例,女307例;BMI(22.69±2.50)kg/m^(2)。采用自编问卷收集人口学与临床特征资料;采用AS测定仪测量臂踝脉搏波传导速度(brachial ankle pulse wave velocity,baPWV),以baPWV>1400 m/s定义为AS,将患者分为AS组(382例)和非AS组(479例);采用彩色多普勒血流探测仪测量踝肱指数。比较两组之间临床资料的差异,并采用二元多因素logistic回归分析非肥胖人群发生AS的相关因素。结果:非肥胖人群AS的发生率为44.37%(382/861),二元多因素logistic回归分析结果显示,年龄(OR=1.11,95%CI 1.09~1.14)、收缩压(OR=1.09,95%CI 1.07~1.10)、脂肪肝(OR=1.82,95%CI 1.15~2.88)是AS的危险因素,BMI(OR=0.86,95%CI 0.80~0.92)是AS的保护因素。结论:非肥胖人群AS的发生率较高,需要重点关注高龄、高收缩压、脂肪肝和低体重人群。Obstractive The aim of this study was to explore the incidence and related risk factors of arteriosclerosis(AS)in nonobese individuals in Meishan,Nanjing.Methods A total of 861 nonobese individuals,aged 24-84 years,with an average age of(51.4±9.49)years,in the Nanjing Meishan Hospital Physical Examination Center from August 2017 to July 2021 were recruited,including 554 males and 307 females.The average BMI is(22.69±2.50)kg/m^(2).Demography and clinical characteristics were collected by self-designed questionnaires;the brachial ankle pulse wave velocity(baPWV)was measured using an arteriosclerosis tester,the participants were divided into AS group(n=382)and non-AS group(n=479)with baPWV greater than 1400 m/s defined as AS;the ankle brachial index was measured using a color Doppler blood flow detector.Compare the differences in clinical data between two groups,and use binary multivariate logistic regression to analyze the relevant factors for the occurrence of AS in nonobese individuals.Results The incidence of AS in nonobese individuals was 44.37%(382/861).The results of binary multivariate logistic regression analysis showed that age(OR=1.11,95%CI:1.09-1.14),systolic blood pressure(OR=1.09,95%CI:1.07-1.10),fatty liver(OR=1.82,95%CI:1.15-2.88)were risk factors,while body mass index(OR=0.86,95%CI:0.80-0.92)was protective factor.Conclusion The incidence of arteriosclerosis in nonobese individuals is relatively high,and it is necessary to focus on the elderly,SBP,fatty liver,and low weight individuals.

关 键 词：非肥胖人群 动脉硬化 臂踝脉搏波传导速度 

分 类 号：R541[医药卫生—心血管疾病]