Efficacy of acupuncture to regain consciousness in patients with traumatic brain injury: a systematic review and meta-analysis  

作　　者：Lamichhane Narendra Yi-Fan Zhang Zi-Chen Zhang Zhi-Fang Xu Yu Luo Mei-Dan Zhao Tian-Yi Zhao 

机构地区：[1]Research Center of Experimental Acupuncture Science,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China [2]School of Acupuncture and Moxibustion and Tuina,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China [3]School of Medical Technology,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China [4]School of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China

出　　处：《TMR Integrative Medicine》2023年第31期1-11,共11页TMR整合医学

基　　金：supported by the National Natural Science Foundation of China No.82074534;College Students’Innovative Entrepreneurial Training Plan No.202210063027.

摘　　要：Background:Traumatic brain injury(TBI)is a leading cause of death and disability worldwide,and consciousness disorder is a common problem in TBI patients.Acupuncture has been used to improve neurological deficits in patients with TBI.This meta-analysis aims to evaluate the effects and safety of acupuncture in improving consciousness in patients with TBI when compared with other therapies.Methods:A systematic search was conducted in electronic databases PubMed,EMBASE,Web of Science,the Cochrane Central Register of Controlled Trials,Allied and Complementary Medicine Database,WHO International Clinical Trials Registry Platform,ClinicalTrials.gov,and Google Scholar for randomized controlled trials that investigated the effect of acupuncture on patients with TBI.From the inception of databases to March 2023.Results:A total of 653 participants were included in nine trials.We found that acupuncture adjunct to routine treatment significantly improved the wakeup rate of patients in TBI when compared with routine treatment alone(relative risk=1.36,95%confidence interval:1.16 to 1.59,I2=4.78%,P=0).Additionally,we found that acupuncture is significantly associated with reduced impaired consciousness after TBI when adjunct to medicine therapy.As a safe intervention,acupuncture can also improve the activities of daily living for people with TBI(mean difference=15.71,95%confidence interval:9.19 to 22.22,I2=0%,P=0).Conclusion:Acupuncture can improve consciousness and braise wakeup of patients with TBI when adjunct to conventional treatment compared with routine treatment alone.Further high-quality studies are needed to confirm these findings and to determine the optimal acupuncture treatment parameter for TBI.

关 键 词：ACUPUNCTURE CONSCIOUSNESS traumatic brain injury systematic review META-ANALYSIS 

分 类 号：R246[医药卫生—针灸推拿学]