Early stage of radiological expertise modulates resting-state local coherence in the inferior temporal lobe  

作　　者：Minghao Dong Peiming Zhang Weilu Chai Xiaoyan Zhang Bihong TChen Hongmei Wang Jia Wu Chao Chen Yi Niu Jimin Liang Guangming Shi Chenwang Jin 

机构地区：[1]Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education,School of Life Science and Technology,Xidian University,Xi’an City,Shaanxi 710071,China [2]Xian Key Laboratory of Intelligent Sensing and Regulation of tran-Scale Life Information,Xi’an City,Shaanxi 710071,China [3]Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education,School of Artificial Intelligence,Xidian University,Xi’an City,Shaanxi 710071,China [4]City of Hope Medical Center,Duarte City,California 91010,USA [5]Department of Medical Imaging,First Affiliated Hospital of Medical College,Xi’an Jiaotong University,Xi’an City,Shaanxi 710000,China [6]School of Foreign Languages,Northwestern Polytechnical University,Xi’an City,Shaanxi 710071,China [7]PLA Funding Payment Center,Beijing 100000,China [8]School of Electronics and Engineering,Xidian University,Xi’an City,Shaanxi 710071,China

出　　处：《Psychoradiology》2022年第4期199-206,共8页精神影像学（英文）

基　　金：This paper is supported by National Key R&D Program of China(Grant No.2022YFF1202400);the National Natural Science Foundation of China(U19B2030);the Science and Technology Projects of Xi’an,China(No.201809170CX11JC12).

摘　　要：Background The visual system and its inherent functions undergo experience-dependent changes through the lifespan,enabling acquisition of new skills.Previous fMRI studies using tasks reported increased specialization in a number of cortical regions subserving visual expertise.Although ample studies focused on representation of long-term visual expertise in the brain,i.e.in terms of year,monthly-based early-stage representation of visual expertise remains unstudied.Given that spontaneous neuronal oscillations actively encode previous experience,we propose brain representations in the resting state is fundamentally important.Objective The current study aimed to investigate how monthly-based early-stage visual expertise are represented in the resting state using the expertise model of radiologists.Methods In particular,we investigated the altered local clustering pattern of spontaneous brain activity using regional homogeneity(ReHo).A cohort group of radiology interns(n=22)after one-month training in X-ray department and matched laypersons(n=22)were recruited after rigorous behavioral assessment.Results The results showed higher ReHo in the right hippocampus(HIP)and the right ventral anterior temporal lobe(vATL)(corrected by Alphasim correction,P<0.05).Moreover,ReHo in the right HIP correlated with the number of cases reviewed during intern radiologists’training(corrected by Alphasim correction,P<0.05).Conclusions In sum,our results demonstrated that the early stage of visual expertise is more concerned with stabilizing visual feature and domain-specific knowledge into long-term memory.The results provided novel evidence regarding how early-stage visual expertise is represented in the resting brain,which help further elaborate how human visual expertise is acquired.We propose that our current study may provide novel ideas for developing new training protocols in medical schools.

关 键 词：visual expertise resting state fMRI RADIOLOGISTS inferior temporal cortex 

分 类 号：R81[医药卫生—放射医学]