1例多药联用致室性心律失常的药学监护  

Pharmaceutical care of one case of malignant arrhythmia induced by multidrug combination

作　　者：郑金凤[1] 王景红[1] ZHENG Jinfeng;WANG Jinghong(Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China)

机构地区：[1]中国中医科学院望京医院药学部,北京100102

出　　处：《中国药物警戒》2023年第11期1279-1281,1285,共4页Chinese Journal of Pharmacovigilance

基　　金：中国中医科学院望京医院自主选题(WJYY-ZZXT-2023-18);北京市中医管理局北京市第三批中药骨干人才培养项目(京中医科字[2021]161号)。

摘　　要：目的 通过1例心衰合并肺部感染应用多种药物致尖端扭转型室速患者的病例介绍,探讨临床药师开展危重症患者药学服务及严重不良反应防范的切入点。方法 临床药师参与1例多药联用致恶性心律失常治疗过程,协助医生识别可疑药物,处理药源性尖端扭转型室性心动过速(TdP)并对主要药物治疗实施药学监护。结果 临床药师协助医师调整用药方案,对严重不良反应采取有效措施,取得良好效果。结论 临床药师参与治疗团队,以药品不良反应为切入点,对重症患者开展药学监护,可有效保障患者用药安全。Objective To explore the entry point of clinical pharmacists to carry out pharmaceutical care for critically ill patients and prevent serious adverse reactions through the introduction of a case of a patient with heart failure complicated with pulmonary infection induced by multi-drug tip torsion ventricular tachycardia.Methods Clinical pharmacists participated in the treatment of a case of malignant arrhythmia caused by multi-drug combination,assisted doctors in identifying suspicious drugs,dealing with drug-induced TdP and implementing pharmaceutical care.Results Clinical pharmacists assisted physicians to adjust the medication regimen and take effective measures for serious adverse reactions,which achieved good results.Conclusion Clinical pharmacists can effectively ensure the safety of medication by participating in the treatment team,taking pharmacy as the breakthrough point and acting as the assistant of doctors.

关 键 词：间断扭转型室速 QT间期延长 药学监护 药品不良反应 多药联用 

分 类 号：R994.11[医药卫生—毒理学]