一种水溶磁性材料的制备及对盐酸小檗碱的提取  

Preparation of a water-soluble magnetic material and extraction of berberine hydrochloride

作　　者：张昀[1] 裴书杨 刘星妤 尤梦瑶 江沛琳 刘路[1] ZHANG Yun;PEI Shuyang;LIU Xingyu;YOU Mengyao;JIANG Peilin;LIU Lu(Pharmaceutical College,Henan University,Kaifeng 475001,Henan,China)

机构地区：[1]河南大学药学院,河南开封475001

出　　处：《化学研究》2023年第6期478-481,共4页Chemical Research

基　　金：河南省高等学校大学生创新训练计划项目(20221020005);河南省科技厅科技发展计划项目(212102311043)。

摘　　要：首次以FeCl_(3)、淀粉、柠檬酸为原料,采用直接水热法,一步合成了水溶性Fe_(3)O_(4)NPs,发现反应的pH对Fe_(3)O_(4)NPs的磁性影响较大,淀粉加入量对Fe_(3)O_(4)NPs的溶解性影响较大。实验结果表明,制备的Fe_(3)O_(4)NPs水溶液浓度较高时,磁铁可以直接吸引水溶液。包覆在外层的羧基,使得Fe_(3)O_(4)NPs可用于盐酸小檗碱的提取,提取率达55.4%。Fe_(3)O_(4) NPs with good water solubility were synthesized by the direct hydrothermal method using FeCl 3,starch and citric acid for the first time.The reaction pH has a great impact on the magnetic property,and the amount of starch has influence on solubility of Fe_(3)O_(4) NPs.The results show that the aqueous solution of Fe_(3)O_(4) NPs can be directly adsorbed by magnets when the concentration is high.The carboxyl group coated in the outer layer makes Fe_(3)O_(4) NPs available for the extraction of berberine hydrochloride,with the extraction rate of 55.4%.

关 键 词：水溶纳米Fe_(3)O_(4) 制备 盐酸小檗碱 

分 类 号：O61[理学—无机化学]