左旋甲状腺素片治疗妊娠期亚临床甲状腺功能减退症对甲状腺功能、妊娠结局的影响观察  

Effect of levothyroxine tablets on thyroid function and pregnancy outcome in the treatment of subclinical hypothyroidism during pregnancy

作　　者：周美玲 Zhou Meiling(Department of Obstetrics,Pingguo People's Hospital,Baise 531499,China)

机构地区：[1]平果市人民医院产科,广西百色531499

出　　处：《实用妇科内分泌电子杂志》2023年第21期78-80,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨左旋甲状腺素片治疗妊娠期亚临床甲状腺功能减退症(SCH)对甲状腺功能、妊娠结局的影响。方法选取46例SCH患者,根据治疗方法不同将患者分为对照组与研究组,每组23例。对照组采用常规处理,研究组采用左旋甲状腺素片治疗。比较两组甲状腺功能、妊娠结局。结果研究组患者治疗后游离三碘甲状腺原氨酸(FT_(3))、游离甲状腺素(FT_(4))指标高于对照组、外周血清促甲状腺激素(TSH)、抗甲状腺过氧化物酶抗体(TPOAb)指标低于对照组(P<0.05)。研究组患者不良妊娠结局发生率13.04%低于对照组的60.87%(P<0.05)。结论SCH患者口服左旋甲状腺素片治疗可改善甲状腺功能,降低不良妊娠结局风险。Objective To investigate the effects of levothyroxine tablets on thyroid function and pregnancy outcome in the treatment of subclinical hypothyroidism(SCH)during pregnancy.Methods 46 SCH patients were selected and divided into control group and study group according to different treatment methods,with 23 cases in each group.The control group was treated with routine treatment,and the study group was treated with levothyroxine tablets.The clinical efficacy of the two groups was compared.Results After treatment,the free triodothyronine(FT_(3))and free thyroxine(FT_(4))indexes in the study group were higher than those in the control group,and the peripheral blood thyrotropin(TSH)and anti-thyroid peroxidase antibody(TPOAb)indexes in the study group were lower than those in the control group(P<0.05).The incidence of adverse pregnancy outcomes in the study group was 13.04%lower than that in the control group 60.87%(P<0.05).Conclusion Oral levothyroxine tablets in SCH patients can improve thyroid function and reduce the risk of adverse pregnancy outcomes.

关 键 词：左旋甲状腺素片 妊娠期亚临床甲状腺功能减退症 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]