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作 者:陆靖 蒋例君 但晓霞 甘露 罗尧尧 陈珊 LU Jing;JIANG Lijun;DAN Xiaoxia;GAN Lu;LUO Yaoyao;CHEN Shan(Guangxi International Zhuang Medical Hospital,Nanning,Guangxi,China 530201)
出 处:《中国药业》2023年第S01期342-345,共4页China Pharmaceuticals
摘 要:目的探讨Ⅰ类手术切口感染患者的病原学特征和感染因素。方法回顾性分析医院2020年1月至2022年1月收治的3971例进行Ⅰ类手术患者的临床资料,统计患者的年龄、性别、基础疾病、是否急诊、恶性肿瘤、术前感染、文化程度、生命指标、围术期营养状况、手术时间等,记录患者的病原菌感染情况,并采用Logistic回归分析感染因素。结果3971例患者中,切口感染患者25例,切口感染率为0.63%。致病菌包括革兰阴性菌、大肠埃希菌、革兰阳性菌、葡萄球菌、肠球菌、其他,分别占44.00%,24.00%,12.00%,8.00%,8.00%,4.00%。Logistic多因素分析结果显示,Ⅰ类手术切口感染的影响因素包括尿管插管时间、住院时间、呼吸机使用时间、存在基础疾病、体质量指数、中心静脉插管时间、抗菌药物使用时间(P<0.05)。结论患者存在基础疾病、抗菌药物和呼吸机使用时间过长会增加院内感染风险,临床应用时必须规范使用抗菌药物,加强管理流程,预先对潜在危险因素进行干预。Objective To investigate the pathogenetic characteristics and infection factors of patients with classⅠsurgical incision infection.Methods The clinical data of 3971 patients admitted to the hospital from January 2020 to January 2022 who underwent classⅠsurgery were retrospectively analyzed,the patients'age,gender,underlying disease,whether emergency,malignant tumor,preoperative infection,literacy level,vital indexes,perioperative nutritional status,and duration of the surgery were counted,the patients'pathogenic bacterial infections were recorded,and the infection factors were analyzed by Logistic regression.Results Among 3971 patients,25 patients had incisional infections,and the incisional infection rate was 0.63%.The causative organisms included Gram-negative,Escherichia coli,Gram-positive,staphylococcus,enterococci,and others,which accounted for 44.00%,24.00%,12.00%,8.00%,8.00%,and 4.00%,respectively.The results of the Logistic regression analysis showed that the influencing factors of incision infections of classⅠsurgery included the time of urinary catheter intubation,the length of hospitalization,and the time of ventilator use,presence of underlying diseases,body mass index,central venous cannulation time,and antimicrobial drug use time(P<0.05).Conclusion The presence of basic diseases,antimicrobial drugs and prolonged ventilator use in patients increase the risk of nosocomial infections,and the clinical application must standardize the use of antimicrobial drugs,strengthen the management process,and intervene in advance for potential risk factors.
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