柴芩承气汤在以腹痛为症状表现的肝胆湿热型急性胰腺炎患者中的应用效果  

Application Effect of Chaiqin Chengqi Decoction in Patients with Liver and GallBladder Dampness Heat Type Acute Pancreatitis Characterized by Abdominal Pain

作　　者：陈建辉 涂振攀 陈莹 CHEN Jianhui;TU Zhenpan;CHEN Ying(Fujian Province Datian County General Hospital Inner Three Districts,Sanming 366100,China)

机构地区：[1]福建省大田县总医院内三区,福建三明366100

出　　处：《中国医药指南》2023年第34期122-124,共3页Guide of China Medicine

摘　　要：目的分析柴芩承气汤在以腹痛为症状表现的肝胆湿热型急性胰腺炎患者中的应用效果。方法本研究以福建省大田县总医院消化内科于2020年1月至2023年2月接收的105例以腹痛为症状表现的肝胆湿热型急性胰腺炎患者作为观察对象。利用最新统计学软件生成随机序列后予以分为对照组及研究组,两组分别有52例、53例。对照组采取常规治疗方式,研究组在对照组的基础上给予柴芩承气汤进行治疗。治疗完成后,对比两组研究对象的临床治疗效果、各项临床时间观察指标、C反应蛋白(CRP)、血清淀粉酶(AMY)、血清脂肪酶(LPS)水平。结果对照组临床治疗总有效率(78.85%)低于研究组(94.34%)(χ^(2)=4.194;P<0.05);研究组围手术期各不良症状消失时间均少于对照组(t=7.925,3.728,4.201,2.719;P<0.05);对照组C反应蛋白、血清淀粉酶和血清脂肪酶均高于研究组(t=33.785,1.893,6.031;P<0.05)。结论对于以腹痛为症状表现的肝胆湿热型急性胰腺炎患者而言,在常规治疗的同时采用柴芩承气汤能明显提升临床治疗效果,缩短首次排气、进食、排便和腹痛症状表现的时间,调节血清LPS、AMY水平。Objective To analyze the application effect of Chaiqin Chengqi Decoction in patients with acute pancreatitis caused by dampness and heat of liver and gallbladder with abdominal pain.Methods 105 patients with damp-heat acute pancreatitis of liver and gallbladder with abdominal pain were enrolled in Department of Gastroenterology,Datian County General Hospital,Fujian Province from January 2020 to February 2023.Using the latest statistical software to generate random sequences,they were divided into control group and study group,52 cases and 53 cases in each group.The control group received conventional treatment,and the study group was given Chaiqin Chengqi Decoction on the basis of the control group.After the completion of treatment,the clinical therapeutic effect,clinical time observation indexes,C-reactive protein(CRP),serum amylase(AMY),and serum lipase(LPS)levels of the two groups were compared.Results The total effective rate of the control group(78.85%)was lower than that of the study group(94.34%).The difference was(χ^(2)=4.194,P<0.05);The time for all adverse symptoms to disappear during perioperative period in the study group was less than that in the control group(t=7.925,3.728,4.201,2.719,P<0.05);C-reactive protein,serum amylase and serum lipase in control group were higher than those in study group(t=33.785,1.893,6.031,P<0.05).Conclusions For patients with acute pancreatitis of damp-heat of liver and bile with abdominal pain,Chaiqin Chengqi decoction combined with conventional treatment can significantly improve the clinical therapeutic effect,shorten the time of first exhaust,eating,defecation and abdominal pain symptoms,and regulate the levels of serum LPS and AMY.

关 键 词：急性胰腺炎 肝胆湿热型 腹痛 柴芩承气汤 胃肠激素 

分 类 号：R657.51[医药卫生—外科学]