成人隐匿性自身免疫糖尿病的研究进展  

Research progress of latent autoimmune diabetes in adults

作　　者：张华(综述) 陈英剑(审校) ZHANG Hua;CHEN Yingjian(Department of Clinical Laboratory,the 960th Hospital of Joint Logistic Support Force of PLA,Ji'nan,Shandong 250031,China)

机构地区：[1]中国人民解放军联勤保障部队第九六〇医院检验科,山东济南250031

出　　处：《检验医学与临床》2023年第23期3537-3540,共4页Laboratory Medicine and Clinic

摘　　要：成人隐匿性自身免疫糖尿病是一种进展缓慢的器官特异性自身免疫疾病,由免疫系统攻击自身胰岛B细胞所致。该疾病早期有1型糖尿病的自身抗体谱,可不依赖胰岛素治疗,故极易被误诊为2型糖尿病,后期发展为胰岛素依赖。目前临床对该病的诊疗仅提出专家共识,尚无权威性指南。该文从其流行病学、发病机制、临床特征、诊断标准及治疗等方面进行综述,以期为该病的临床诊疗提供理论依据。Latent autoimmune diabetes in adults is a slowly progressive organ-specific autoimmune disease caused by the immune system attacking its own islet B cells.In the early stage of the disease,there is an autoantibody spectrum of type 1 diabetes,which is independent of insulin treatment,so it is easy to be misdiagnosed as type 2 diabetes,and later develops into insulin dependence.At present,only expert consensus has been put forward for the diagnosis and treatment of this disease,and there is no authoritative guideline.This article reviews its epidemiology,pathogenesis,clinical features,diagnostic criteria and treatment in order to provide theoretical basis for the clinical diagnosis and treatment of this disease.

关 键 词：成人隐匿性自身免疫糖尿病 自身免疫 隐匿性 诊疗 

分 类 号：R587.1[医药卫生—内分泌]