利托君及硫酸镁运用于胎盘前置状态先兆流产患者治疗的效果研究  

Curative Effect Study on Litodrine and Magnesium Sulfate on Threatened Abortion Patients with Placenta Previa

作　　者：饶芸 胡璇 索海燕 张新清 RAO Yun;HU Xuan;SUO Haiyan;ZHANG Xinqing(Department of Obstetrics,Union Shenzhen Hospital,Huazhong University of Science and Technology,Shenzhen,Guangdong 518052)

机构地区：[1]华中科技大学协和深圳医院产科,广东深圳518052

出　　处：《智慧健康》2023年第21期128-131,共4页Smart Healthcare

摘　　要：目的 探讨利托君及硫酸镁运用于胎盘前置状态先兆流产患者治疗的效果研究。方法 将2021年1月-2022年6月在本院产科治疗的72例胎盘前置状态先兆流产患者随机分为对照组和观察组,每组各36例,其中对照组使用硫酸镁治疗,观察组使用利托君治疗,对比两组的临床疗效、症状改善各指标、不良反应、妊娠结局。结果 观察组治疗有效率明显高于对照组,组间差异有统计学意义(P<0.05);观察组宫缩消失时间、先兆流产症状消失时间、阴道出血持续时间、妊娠延长时间均短于对照组,阴道出血停止率、妊娠至足月率均高于对照组,组间差异有统计学意义(P<0.05);观察组肠胃不适、头痛、血糖升高、心动过缓等不良反应发生率明显低于对照组,组间差异有统计学意义(P<0.05);观察组阴道分娩率、新生儿Apgar评分明显高于对照组,新生儿体重均大于对照组,组间差异有统计学意义(P<0.05);观察组产后出血率、新生儿窒息率均低于对照组,组间差异不大,无统计学意义(P>0.05)。结论 利托君用于胎盘前置状态先兆流产的治疗效果更好,能有效缩短症状消失时间,延长妊娠时间,提高足月妊娠及阴道分娩率,提高新生儿质量,有助于改善妊娠结局,且安全性更高,有积极的临床意义。Objective to investigate curative effect of ritodrine and magnesium sulfate on threatened abortion patients with placenta previa.Methods The paper chose 72 patients with threatened abortion of placenta previa in our obstetrics department from January 2021 to June 2022,and divided them into two groups randomly.Control group was treated with magnesium sulfate,while observation group with rituximab.Clinical effect,symptom improvement indicators,adverse reactions,and pregnancy outcomes between two groups were compared.Results Effective rate of treatment in observation group was 94.44%,significantly higher than 72.22%in control group(P<0.05).Disappearance time of uterine contractions,threatened abortion symptoms,prolongation time of pregnancy in observation group was longer than control group.Stopping rate of vaginal bleeding and pregnancy term rate was higher than control group(P<0.05).Incidence of adverse reactions such as gastrointestinal discomfort,headache,elevated blood sugar,and bradycardia in observation group was significantly lower than control group(P<0.05).Vaginal delivery rate in observation group was significantly higher than control group,the Apgar scores and weight of newborns were higher than control group(P<0.05),Postpartum bleeding and neonatal asphyxia rate was lower than control group,there was no statistical significance(P>0.05).Conclusion Ritodrine can achieve better effect in treatment of threatened abortion with placenta previa,can shorten symptom disappearance time,prolong pregnancy time,increase full term pregnancy and vaginal delivery rate,improve quality of newborns effectively,and improve pregnancy outcome,which has higher safety and positive clinical significance.

关 键 词：胎盘前置 先兆流产 利托君 硫酸镁 治疗效果 

分 类 号：R714.21[医药卫生—妇产科学]