藏药矮紫堇的化学成分及药理作用研究进展  

Research progress in chemical components and pharmacological effects of the Tibetan medicine Aizijin

作　　者：李岳庭 秦民坚[1] 戴轶群 李啟恩 谢国勇[1] LI Yue-ting;QIN Min-jian;DAI Yi-qun;LI Qi-en;XIE Guo-yong(Department of Resources Science of Traditional Chinese Medicines,School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 210009,China;Tibetan Medicine Research Center/State Key Laboratory of Tibetan Medicine Research and Development,Tibetan Medical College,Qinghai University,Xining 810016,China)

机构地区：[1]中国药科大学中药学院,南京210009 [2]青海大学藏医学院藏医药研究中心/藏药新药开发国家重点实验室,西宁810016

出　　处：《中国新药杂志》2023年第21期2140-2146,共7页Chinese Journal of New Drugs

基　　金：中央高校基本科研业务费重点项目(2632022ZD20);青海省自然科学基金面上项目(2019-ZJ-907)。

摘　　要：矮紫堇是我国的传统藏药,其基原为罂粟科植物尼泊尔黄堇和尖突黄堇,具有悠久的应用历史。其性凉味苦,民间多用于治疗肠炎、脉管炎及“木布”等疾病。现代研究表明,矮紫堇含有生物碱、黄酮、五环三萜等多种有效成分,具有解热、镇痛、抗炎及抗氧化等功效,可用于治疗高原性红细胞增多症。本文对矮紫堇的化学成分和药理作用进行了综述,并对其未来发展进行了展望,以期为矮紫堇的合理开发利用及资源保护提供一定的科学依据。Aizijin is a traditional Tibetan medicine in China from Corydalis hendersonii Hemsl.and Corydalis mucronifera Maxim.with a long history of application and its property is mainly cool and tastes bitter.It is commonly used to treat enteritis,angiitis,“Mubu”and other diseases in Qinghai-Tibet Plateau.Modern research shows that Aizijin has rich chemical components like alkaloids,flavonoids,pentacyclic triterpenoids and other components and shows antipyretic,analgesic,anti-inflammatory and antioxidant effects,which can be used in the treatment of high altitude polycthemia(HAPC).Through literature research,we reviewed the chemical components and pharmacological effects of Aizijin and forecast its future development,which provides a scientific basis for the further development and resource conservation of Aizijin.

关 键 词：藏药 矮紫堇 化学成分 药理作用 

分 类 号：R961[医药卫生—药理学]