神经导航辅助内镜下经鼻蝶入路切除垂体腺瘤的临床对照  

Clinical Study of Neuronavigation-assisted Endoscopic Transnasal Sphenoid Approach for Resection of Pituitary Tumors

作　　者：谢文友 黄同亨 杨燕汝 刘金阳 XIE Wenyou;HUANG Tongheng;YANG Yanru;LIU Jinyang(Dept.of Neurosurgery,Yangjiang Hospital Affiliated to Guangdong Medical University/Yangjiang City People's Hospital,Yangjiang Guangdong 529500,China)

机构地区：[1]广东医科大学附属阳江医院/阳江市人民医院神经外一科,广东阳江529500

出　　处：《昆明医科大学学报》2023年第11期108-112,共5页Journal of Kunming Medical University

基　　金：广东省阳江市卫生类科技计划基金资助项目(SF2022063)。

摘　　要：目的探讨全麻下神经导航定位辅助内镜下经鼻蝶入路切除垂体腺瘤的临床应用疗效及前景。方法收集阳江市人民医院神经外科2018年9月至2023年4月垂体腺瘤手术患者共68例,分为2组:实验组34例(神经导航定位辅助内镜下经鼻蝶入路切除垂体腺瘤),对照组34例(显微镜经鼻蝶入路切除垂体腺瘤),分析评价2组手术相关指标,并发症指标,手术前后内分泌激素指标。结果肿瘤全切几率在术后影像学对比中实验组高于对照组,差异具有统计学意义(P<0.05)。手术时间、出血量、住院时间、手术出血量及术后患者激素指标对比,实验组低于对照组,差异具有统计学意义(P<0.05)。结论神经导航辅助内镜下经鼻蝶入路切除垂体腺瘤具有创伤小、安全、高效、住院时间短、全切率高等优点,值得临床推广应用。Objective To explore and analyze the clinical application efficacy and prospect of neuronavigation positioning assisted endoscopic transnasal sphenoid approach for resection of pituitary adenomas under general anesthesia.Methods A total of 68 patients who underwent pituitary adenoma surgery at the Neurosurgery Department of Yangjiang People's Hospital from September 2018 to April 2023 were collected and divided into two groups:an experimental group of 34 patients(neuronavigation-assisted endoscopic transsphenoidal approach for pituitary adenoma resection)and a control group of 34 patients(microscopic transsphenoidal approach for pituitary adenoma resection).The surgery-related indicators,complication indicators,and preoperative and postoperative endocrine hormone indicators were analyzed and evaluated in both groups.Results The probability of total tumor resection in the experimental group was significantly higher than that in the control group in postoperative imaging comparison,with statistical significance(P<0.05).The comparison of surgical time,bleeding volume,hospitalization time,surgical bleeding volume,and postoperative patient hormone indicators showed that the experimental group was significantly lower than the control group,and the difference was statistically significant(P<0.05).Conclusions Neuronavigation positioning assisted endoscopic transnasal sphenoid approach for resection of pituitary adenoma has the advantages of small trauma,safety,high efficiency,short hospital stay,and high total resection rate.This represents a novel and effective strategy for wide clinical application.

关 键 词：神经导航 神经内镜 显微镜 垂体腺瘤 

分 类 号：R615[医药卫生—外科学]