基于双能X线吸收仪的骨折风险评估:骨密度以外的因素  

Fracture risk assessment based on dual-energy X-ray absorptiometry:beyond bone mineral density determination

作　　者：传丰宁 周波[2] CHUAN Feng-ning;ZHOU Bo(Department of Endocrinology,Chongqing University Fuling Hospital,Chongqing 408099,China;Department of Endocrinology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆大学附属涪陵医院内分泌科,重庆408099 [2]重庆医科大学附属第一医院内分泌科,重庆400016

出　　处：《中华骨质疏松和骨矿盐疾病杂志》2023年第4期381-387,共7页Chinese Journal Of Osteoporosis And Bone Mineral Research

摘　　要：脆性骨折系骨质疏松症患者最严重的并发症。尽管双能X线吸收测量仪(dual-energy X-ray absorptiometry,DXA)测量的骨密度(bone mineral density,BMD)广泛应用于评估骨折风险,但仅依据BMD测量结果往往会低估骨折风险。近年来,随着DXA技术的快速发展,其实用性已从BMD扩展到其他新功能,如检测寂静性骨折、评估骨质量以及测定体成分等,这为骨折的临床预防及治疗策略提供了新思路。本文对基于DXA除BMD外的其他参数在预测骨折风险方面的研究进展做一综述。Fragility fractures are the most serious complications of patients with osteoporosis.Despite the widely application of bone mineral density(BMD)measured by dual-energy X-ray absorptiometry(DXA)in assessing fracture risk,BMD measurement alone often underestimates the risk of fracture.In recent years,with the rapid development of DXA technology,its clinical applications have extended from BMD analysis to other novel functions,such as detecting silent fractures,evaluating bone quality,and measuring body composition.These advancements provide new insights into the clinical prevention and treatment strategies for fractures.We review the progress on non-BMD parameters derived from DXA for predicting fracture risk.

关 键 词：双能X线吸收测量仪 骨折风险 骨质量 体成分 

分 类 号：R589[医药卫生—内分泌] R681[医药卫生—内科学]