八味安神汤联合针刺内关、神门穴治疗室上性心动过速临床研究  

Clinical Study on Bawei Anshen Decoction Combined with Acupuncture at Neiguan Point and Shenmen Point for Supraventricular Tachycardia

作　　者：孙兵 廖骏 许海斌 SUN Bing;LIAO Jun;XU Haibin(Department of Cardiovascular Medicine,The First People's Hospital of Huzhou,Huzhou Zhejiang 313000,China)

机构地区：[1]湖州市第一人民医院心血管内科,浙江湖州313000

出　　处：《新中医》2023年第21期34-39,共6页New Chinese Medicine

基　　金：浙江省中医药管理局“十三五”重点计划项目(202100266)。

摘　　要：目的:观察八味安神汤联合针刺内关、神门穴治疗室上性心动过速的临床疗效。方法:选择82例室上性心动过速患者,按随机数字表法分为对照组和治疗组各41例。对照组给予常规西医治疗,治疗组在对照组基础上给予八味安神汤联合针刺内关、神门穴治疗。比较2组治疗前后血管性血友病因子(vWF)、血浆血栓素A2 (TXA2)、血清心肌肌钙蛋白(c TnI)、一氧化氮(NO)、肌酸激酶同工酶(CK-MB)、血浆内皮素(ET)、氨基末端脑钠肽前体(NT-proBNP)、T波峰末间期(Tpe)、校正QT离散度(QTcd)、左心室射血分数(LVEF)、心率水平及中医证候积分,并比较2组临床疗效。结果:治疗组一次复律成功率高于对照组(P<0.05),治疗组平均复律时间短于对照组(P<0.05)。治疗后,2组Tpe、QTcd、心率水平均降低(P<0.05),且治疗组低于对照组(P<0.05),2组LVEF水平均升高(P<0.05),且治疗组高于对照组(P<0.05)。治疗后,2组vWF、ET水平均降低(P<0.05),且治疗组低于对照组(P<0.05),2组NO水平均升高(P<0.05),且治疗组高于对照组(P<0.05)。治疗后,2组cTnI、CK-MB、NT-proBNP、TXA2水平均降低(P<0.05),且治疗组低于对照组(P<0.05)。治疗后,2组中医证候积分均降低(P<0.05),且治疗组低于对照组(P<0.05)。治疗组总有效率95.12%,高于对照组80.49%(P<0.05)。结论:八味安神汤联合针刺内关、神门穴治疗室上性心动过速患者,可终止室上性心动过速状态,加速复律,促进心肌复极,改善血管内皮功能指标,降低cTnI、CK-MB、NT-proBNP、TXA2水平,缓解临床症状,提升临床疗效。Objective:To observe clinical effect of Bawei Anshen Decoction combined with acupuncture at Neiguan point(PC6)and Shenmen point(TF4)for supraventricular tachycardia.Methods:A total of 82 cases of patients with supraventricular tachycardia were selected and divided into the reference group and the treatment group according to the random number table method,with 41 cases in each group.The reference group was given conventional western medicine treatment,and the trial group was additionally treated with Bawei Anshen Decoction combined with acupuncture at Neiguan point(PC6)and Shenmen point(TF4)based on the treatment of the reference group.The levels of von Willebrand factors(vWF),thromboxane A2(TXA2)in plasma,cardiac troponin(cTnI)in serum,nitric oxide(NO),creatine kinase isoenzyme(CK-MB),endothelin(ET)in plasma,N-terminal pro-brain natriuretic peptide(NT-proBNP),T peak to end interval(Tpe),corrected QT dispersion(QTcd),left ventricular ejection fraction(LVEF),and heart rate,as well as traditional Chinese medicine(TCM)syndrome scores were compared between the two groups before and after treatment.Clinical effects were compared between the two groups.Results:The initial success rate of cardioversion in the treatment group was higher than that in the reference group(P<0.05),and the mean time of cardioversion in the treatment group was shorter than that in the reference group(P<0.05).After treatment,the levels of Tpe,QTcd,and heart rate in the two groups were decreased(P<0.05),and the levels of Tpe,QTcd,and heart rate in the treatment group were lower than those in the reference group(P<0.05);the levels of LVEF in the two groups were increased(P<0.05),and the LVEF level in the treatment group was higher than that in the reference group(P<0.05).After treatment,the levels of vWF and ET in the two groups were decreased(P<0.05),and the two levels in the treatment group were lower than those in the reference group(P<0.05);the levels of NO in the two groups were increased(P<0.05),and the NO level in the treatment group was h

关 键 词：室上性心动过速 八味安神汤 针刺 终止作用 心肌复极 血管内皮功能 

分 类 号：R541.71[医药卫生—心血管疾病]