兰州市中老年体质与骨质疏松调查  

An investigation on physical condition and osteoporosis in the middle age and elderly in Lanzhou city

作　　者：王兴博[1] 金明霞[1] 胡宁宁[1] 郭士方[1] 陈志信[1] 张辉[1] 台会平[1] 施松波[1] WANG Xing-bo;JIN Ming-xia;HU Ning-ning;GUO Shi-fang;CHEN Zhi-xin;ZHANG Hui;TAI Hui-ping;SHI Song-bo(People's Hospital of Gansu Province,Lanzhou 730000,China)

机构地区：[1]甘肃省人民医院,甘肃兰州730000

出　　处：《中国矫形外科杂志》2023年第21期2009-2012,共4页Orthopedic Journal of China

基　　金：甘肃省卫生健康行业科研计划项目(编号:GSWSHL2020-35);甘肃省自然科学基金项目(编号:21JR7RA596)。

摘　　要：[目的]探讨中老年人年龄、性别和体质指数(body mass index,BMI)与骨质疏松症(osteoporosis,OP)之间关系。[方法]兰州本地居民958人纳入本研究,获取观察对象的体质资料,检测骨密度,并依据诊断标准确定是否OP。对此人群的资料进行描述性分析,以是否OP的二分变量为因变量,其他因素为自变量,行多因素逻辑回归分析,探索OP发生的相关因素。[结果]本组男457人,女501人;年龄40~89岁,平均(61.7±7.5)岁;男性OP检出率为2.7%~21.5%,女性OP检出率11.9%~61.0%。随年龄增加,男性和女性的BMI均呈下降趋势,但差异均无统计学意义(P>0.05);随年龄增加,男性和女性的OP检出率均显著上升(P<0.001)。相同年龄组,男性BMI大于女性,但差异均无统计学意义(P>0.05);但是,相同年龄组男性OP的检出率均显著低于女性(P<0.001)。逻辑回归表明:女性(OR=3.782,95%CI 2.415~5.85,P<0.001),高龄(OR=2.031,95%CI 1.724~2.831,P<0.001)是OP发生的独立危险因素,而大BMI(OR=0.447,95%CI 0.361~0.693,P<0.001)是OP发生的保护因素。[结论]此组人群随年龄增加OP的发生率显著增加,女性OP的发生率显著高于男性。在此人群中,高BMI是OP发生的保护性因素。[Objective] To investigate the relationship between age,sex,body mass index(BMI) and osteoporosis(OP) in middle-aged and elderly people.[Methods] A total of 958 local residents in Lanzhou city were included in this study.The data regarding to the physical condition of the subjects were obtained,bone mineral density(BMD) was detected,based on which whether or not OP was determined according to diagnostic criteria.Descriptive analysis was performed on the data of this population,and multi-factor logistic regression analysis was performed to explore the related factors of OP occurrence with binary variable of OP or not as the dependent variable and other factors as the independent variables.[Results] There were 457 males and 501 females in this population,aged from 40 to 89 years old with a mean(61.7±7.5) years old.OP was detected from 2.7% to 21.5% in the male,while from 11.9% to 61.0% in the female.The BMI of both men and women decreased with age,but the differences were not statistically significant(P>0.05).The OP detection rates increased significantly with age in both males and females(P>0.001).The males had greater BMI than the female in the all age groups,but the differences were not statistically significant(P>0.05).However,the detection rate of OP in males was significantly lower than that in females in all age groups(P<0.001).As results of logistic regression,the females(OR=3.782,95%CI 2.415~5.85,P<0.001) and advanced age(OR=2.031,95%CI 1.724~2.831,P<0.001) were independent risk factor for OP,while greater BMI(OR=0.447,95%CI 0.361~0.693,P<0.001) was a protective factor for the occurrence of OP.[Conclusion] The incidence of OP in this population increases remarkably with age,and is significantly higher in females than in males.In addition,greater BMI is a protective factor for the occurrence of OP in this population.

关 键 词：骨密度 骨质疏松 年龄 性别 体质指数 

分 类 号：R687[医药卫生—骨科学]