不明原因不孕妇女的阴道微生态异常与治疗  

Vaginal microbiota abnormalities in women with unexplained infertility and its treatment

作　　者：黄佳铃 王霞[1] 于凡[1] 李明远 唐袁婷[1] Huang Jialing;Wang Xia;Yu Fan;Li Mingyuan;Tang Yuanting(Department of Laboratory Medicine,West China Second University Hospital,Sichuan University/Key Laboratory of Birth Defects and Related Maternal and Child Diseases,Ministry of Education,Chengdu 610041,China)

机构地区：[1]四川大学华西第二医院检验科出生缺陷与相关妇儿疾病教育部重点实验室,成都610041

出　　处：《中华预防医学杂志》2023年第11期1813-1819,共7页Chinese Journal of Preventive Medicine

基　　金：四川省自然科学基金 (2023NSFSC1602)。

摘　　要：阴道微生态是一个复杂而动态的环境,在女性的健康生殖中起着重要作用。不明原因不孕症的发生机制尚不明确,阴道微生态失调和低稳定性可能与不明原因不孕有关,服用益生菌复合制剂恢复正常阴道微生态可能是治疗不明原因不孕症的一种安全且天然的方法。本文就国内外治疗不明原因不孕使用的益生菌复合制剂包含菌种的分离部位、复合制剂的使用方式、疗程以及最后的治疗效果进行综述,旨在为益生菌复合制剂治疗不明原因不孕在临床上的应用提供依据。The vaginal microbiota is a complex and dynamic environment that plays an important role in the healthy reproduction of women.The mechanism of unexplained infertility is not yet clear,and the imbalance and low stability of vaginal microbiota may be related to unexplained infertility.Taking probiotic composite preparations to restore normal vaginal microbiota may be a safe and natural method for treating unexplained infertility.This article reviews the probiotic composite preparations used in the treatment of unexplained infertility both domestically and internationally,including the isolation site of the bacterial species,the use method of the composite preparation,the course of treatment,and the final therapeutic effect,aiming to provide a basis for the clinical application of probiotic composite preparations in the treatment of unexplained infertility.

关 键 词：女性不孕 生态学 微生态 益生菌治疗 

分 类 号：R711.6[医药卫生—妇产科学]