骨质疏松性椎体压缩骨折患者生存质量对心理痛楚的影响  

Effect of quality of life on psychological distress in patients with osteoporotic vertebral compression fractures

作　　者：耿贵敏 舒丽 陈静 罗顺梅 徐康兰 王艳 刘国雄 GENG Guimin;SHU Li;CHEN Jing;LUO Shunmei;XU Kanglan;WANG Yan;LIU Guoxiong(Spine Surgery,Zunyi First People’s Hospital(the Third Affiliated Hospital of Zunyi Medical University),Zunyi 563000,China)

机构地区：[1]遵义市第一人民医院(遵义医科大学第三附属医院)脊柱外科,贵州遵义563000

出　　处：《中国骨质疏松杂志》2023年第11期1610-1614,1631,共6页Chinese Journal of Osteoporosis

基　　金：贵州省卫生健康委科学技术基金项目(gzwkj2022-367)。

摘　　要：目的探究自我感受负担在骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fractures,OVCF)患者生存质量与心理痛楚之间的潜在中介作用,以及家庭支持对中介过程的调节作用。方法采用简明健康调查量表、自我感觉负担量表、心理痛楚量表、家庭支持自评分量表对2021年2月至2023年1月遵义市第一人民医院收治的225例OVCF患者进行问卷调查。采用Process插件构建结构方程模型及Bootstrapp检验确定中介效应和调节效应的显著性。结果生存质量对心理痛楚的负向预测作用显著(β=-11.173,SE=0.053,t=-11.173,P<0.001)。自我感受负担在生存质量和心理痛楚之间发挥部分中介作用(β=-0.176,SE=0.050,95%CI:-0.283~-0.088),中介效应占比29.73%。自我感受负担与家庭支持的交互项对心理痛楚的影响显著(β=-0.029,P<0.05,95%CI:-0.057~-0.001),低水平的家庭支持调节自我感受负担在生存质量与心理痛楚之间有中介过程(β=0.424,P<0.05,95%CI:-0.333~-0.099)。结论自我感受负担是OVCF患者生存质量和心理痛楚的重要中介因素,其中受到家庭支持的调节,低家庭支持时,OVCF患者的自我感受负担增加会加剧心理痛楚。Objective To explore the potential mediating effect of self-perceived burden between quality of life and psychological distress in patients with osteoporotic vertebral compression fractures(OVCF),and the moderating effect of family support on the mediating process.Methods A questionnaire survey was conducted in 225 patients with OVCF admitted to our hospital from February 2021 to January 2023 by using the concise health survey scale,the self-perceived burden scale,the psychological pain scale,and the family support self-rating scale.Process plug-in and Bootstrapp test were used to construct structural equation model and to determine the significance of mediating effect and moderating effect.Results The negative predictive effect of quality of life on psychological distress was significant(β=-11.173,SE=0.053,t=-11.173,P<0.001).Self-perceived burden played a partial mediating role between quality of life and psychological distress(β=-0.176,SE=0.050,95%CI:-0.283--0.088),and the mediating effect accounted for 29.73%.The interaction between self-perceived burden and family support had a significant effect on psychological distress(β=-0.029,P<0.05,95%CI:-0.057--0.001).Low level of family support regulated the mediating process of self-perceived burden between quality of life and psychological distress(β=0.424,P<0.05,95%CI:-0.333--0.099).Conclusion Self-perceived burden is an important intermediary factor for the quality of life and psychological distress in OVCF patients,which is regulated by family support.When family support is low,the increase of self-perceived burden in OVCF patients may aggravate psychological pain.

关 键 词：骨质疏松性椎体压缩骨折 生存质量 心理痛楚 自我感受负担 家庭支持 

分 类 号：R587.1[医药卫生—内分泌]