2型糖尿病微血管病变的影响因素分析  

Analysis of Influencing Factors of Microangiopathy in Type 2 DiabetesMellitus

作　　者：李才珍 陈丽玲 钟玚 LI Caizhen;CHEN Liing;ZHONG chang(Department of Laboratory,Longyan People's Hospital,Longyan,Fujian Province,364000 China)

机构地区：[1]龙岩人民医院检验科,福建龙岩364000

出　　处：《糖尿病新世界》2023年第19期160-163,共4页Diabetes New World Magazine

摘　　要：目的探究2型糖尿病微血管病变的影响因素。方法从2021年1月—2022年12月龙岩人民医院收治的2型糖尿病患者中,随机抽取210例作为研究对象,根据微血管病变情况分组,分为对照组(无微血管病变,105例)与观察组(存在微血管病变组,105例),收集患者性别、年龄、病程、血压、身高、体质指数、血糖、血脂及血常规,分析影响患者微血管病变的影响因素。结果2型糖尿病患者年龄、病程、收缩压、血肌酐、糖化血红蛋白、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、中性粒细胞计数、淋巴细胞计数以及中性粒细胞技术与淋巴细胞计算的比值(neutrophil-lymphocyte ratio,NLR)均为引发患者微血管病变的危险因素(P<0.05)。结论影响2型糖尿病患者微血管病变的危险因素包括患者年龄、病程、收缩压、血肌酐、糖化血红蛋白、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、中性粒细胞计数、淋巴细胞计数以及NLR等,所以患者需要有效观察相关指标的变化,做好微血管病变预防措施。Objective To investigate the influencing factors of microangiopathy in type 2 diabetes mellitus.Methods From January 2021 to December 2022,210 patients with type 2 diabetes admitted to Longyan People's Hospital were randomly selected as the research objects.According to the microangiopathy,they were divided into control group(no microangiopathy,105 cases)and observation group(microangiopathy group,105 cases).The gender,age,course of dis-ease,blood pressure,height,body mass index,blood glucose,blood lipid and blood routine of the patients were col-lected,and the influencing factors of microangiopathy were analyzed.Results Age,course of disease,systolic blood pressure,serum creatinine,glycosylated hemoglobin,total cholesterol,triglyceride,low density lipoprotein cholesterol,neutrophil count,lymphocyte count and neutrophil-lymphocyte ratio(NLR)were all risk factors for microvascular dis-ease in patients with type 2 diabetes(P<0.05).Conclusion Risk factors for microangiopathy in patients with type 2 diabetes mellitus include age,disease duration,systolic blood pressure,creatinine,glycosylated hemoglobin,total cho-lesterol,triacylglycerol,low-density lipoprotein cholesterol,neutrophil count,lymphocyte count,and NLR,and there-fore patients need to be effectively observed for changes in the relevant indexes and take preventive measures against microangiopathy.

关 键 词：2型糖尿病 微血管病变 影响因素 分析 

分 类 号：R446.1[医药卫生—诊断学]