评价七氟醚吸入麻醉和艾司氯胺酮静脉麻醉用于手术患者的效果  

Effects of Sevoflurane Inhalation Anesthesia and Esketamine Intravenous Anesthesia in Patients Undergoing Surgery

作　　者：李婷 孙婉婉 高福寅 LI Ting;SUN Wanwan;GAO Fuyin(Department of Anesthesiology,Juye County People's Hospital,Heze,Shandong Province,274700 China)

机构地区：[1]巨野县人民医院麻醉科,山东菏泽274700

出　　处：《系统医学》2023年第17期46-48,56,共4页Systems Medicine

摘　　要：目的对比七氟醚吸入麻醉和艾司氯胺酮静脉麻醉用于手术患者的效果。方法选取2021年1月—2023年1月巨野县人民医院收治的72例患者作为研究对象,根据随机数表法分为对照组和观察组,每组36例。对照组采用艾司氯胺酮进行静脉麻醉,观察组采用七氟醚吸入麻醉,比较两组患者麻醉效果。结果术前两组患者心率比较,差异无统计学意义(P>0.05);术中、术后,观察组心率高于对照组,差异有统计学意义(P<0.05)。观察组拔管时间、睁眼时间均短于对照组,差异有统计学意义(P<0.05)。术前,两组患者认知功能评分比较,差异无统计学意义(P>0.05);术后观察组各时间点认知功能评分均高于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为5.56%,低于对照组的8.33%,但差异无统计学意义(χ^(2)=0.000,P=1.000)。结论在手术麻醉中,七氟醚吸入麻醉和艾司氯胺酮静脉麻醉相比,前者对患者体征的影响更小,而后苏醒更快,术后早期认知功能恢复好。Objective To compare the effects of Sevoflurane inhalation anesthesia and Esketamine intravenous anes-thesia in surgical patients.Methods A total of 72 patients admitted to Juye County People's Hospital from January 2021 to January 2023 were selected as research objects and divided into control group and observation group accord-ing to random number table method,with 36 patients in each group.The control group was given Esketamine intrave-nous anesthesia,and the observation group was given Sevoflurane inhalation anesthesia.The anesthetic effect of the two groups was compared.Results There was no statistically significant difference in heart rate between the two groups before surgery(P>0.05);during and after operation,the heart rate of observation group was higher than that of control group,the difference was statistically significant(P<0.05).The extubation time and eye opening time in the ob-servation group were shorter than those in the control group,and the difference was statistically significant(P<0.05).Before operation,there was no statistically significant difference in cognitive function scores between the two groups(P>0.05);the cognitive function scores of the observation group were higher than those of the control group at all time points after operation,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 5.56%,lower than that in the control group(8.33%),but the difference was not statistically significant(χ^(2)=0.000,P=1.000).Conclusion In surgical anesthesia,Sevoflurane inhalation anesthesia had less impact on patients'physical signs,faster subsequent recovery and better early postoperative cognitive function than Esket-amine intravenous anesthesia.

关 键 词：七氟醚吸入麻醉 艾司氯胺酮静脉麻醉 手术患者 体征波动 认知功能 安全性 

分 类 号：R614[医药卫生—麻醉学]