某丙型肝炎相关干预研究的随访及影响因素分析  

Follow-up in a intervention study related to HCV and influencing factors

作　　者：芦明月 米国栋 于飞 王晓冬 任仙龙 Lu Mingyue;Mi Guodong;Yu Fei;Wang Xiaodong;Ren Xianlong(General Office of Beijing Center for Disease Prevention and Control,Beijing 100013,China;Department of Medical Affairs,Danlan Beijing Media Limited,Beijing 100020,China;General Office of Tongle Center for Health Consultation and Service,Chengdu 610011,China)

机构地区：[1]北京市疾病预防控制中心办公室,100013 [2]淡蓝(北京)文化传媒有限公司医学事务部,100020 [3]成都同乐健康咨询服务中心办公室,610011 [4]北京市疾病预防控制中心性病艾滋病防治所,100013

出　　处：《国际病毒学杂志》2023年第5期370-375,共6页International Journal of Virology

基　　金：HIV/HCV No Co-Infection(NoCo)Program(IN-US-987-5557)。

摘　　要：目的描述某基于社交软件开展的丙型肝炎(HCV)相关干预研究的随访情况,以及对随访的影响因素进行分析。方法选取该项干预研究中研究对象的基线数据(包括一般人口学信息、性行为情况、HIV检测情况和既往HCV了解情况等)和随访情况进行分析。采用χ^(2)检验比较不同特征调查对象随访率的差异,采用logistic回归分析影响成功随访的相关因素。结果共纳入研究对象1180名,年龄主要集中在19~29岁,占49.1%(579名);近6个月口交和肛交性行为均发生过的比例为70.5%(832名);多性伴的情况较多,占56.3%(664名)。237名研究对象成功接受随访,随访率为20.1%,单因素分析结果显示,年龄越高、听说过HCV、既往进行过HIV检测者随访率更高;回归分析结果显示,与19~29岁组相比,40~49岁组和50岁以上组成功接受到随访的可能性更高,OR(95%CI)值分别为1.7(1.1~2.7)和3.5(2.0~6.2);与既往未听说过丙肝者相比,既往听说过丙肝者接受到随访的可能性更高,OR(95%CI)值为1.6(1.2~2.3);而与既往未检测过HIV者相比,检测过HIV者成功接受到随访的可能性更高,OR(95%CI)值为1.9(1.1~3.1)。结论基于线上的HCV健康行为干预的随访率仍有待提高,随访过程中应更多关注年龄较轻者,并应充分利用HIV咨询检测等多种手段宣传HCV的相关知识,提高知晓率,从而进一步提高随访效果。Objective To describe the follow-up of a hepatitis C(HCV)related intervention study based on social software,and analyze the associated factors of the follow-up.Methods The baseline data(including general demographic information,sexual behavior,HIV testing,and previous HCV knowledge)and follow-up of the intervention study were analyzed.Chi-square test was used to compare the difference of successful follow-up rate between different characteristics,and logistic regression was used to analyze the associated factors affecting successful follow-up.Results A total of 1180 subjects were included in this intervention study,and the age group was mainly 19-29 years old,accounting for 49.1%(579).The proportion of having both oral and anal sex in the past 6 months was 70.5%(832).Multiple sexual partners was common,accounting for 56.3%(664).Two hundred and thirty-seven participants were followed up successfully and rate of follow-up was 20.1%.Univariate analysis showed that the rate of follow-up among persons with older in age,heard about HCV and previous HIV testing were higher.The results of regression analysis showed that compared with the 19-29 years old group,the 40-49 years old group and the group of 50 years old and above were more likely to had successful follow-up,and the OR(95%CI)values were 1.7(1.1-2.7)and 3.5(2.0-6.2),respectively.Compared with those who had never heard of hepatitis C,those who had heard of hepatitis C were more likely to accept follow-up,with an OR(95%CI)value of 1.6(1.2-2.3).Compared with those who had not been tested for HIV previously,those who had been tested for HIV were more likely to be successfully followed up,with an OR(95%CI)value of 1.9(1.1-3.1).Conclusions The follow-up rate in an online health intervention program of HCV should be improved and pay more attention to the younger people during the follow-up.HIV counseling and testing and other means should be fully applied to promote HCV knowledge,improve the awareness rate,for more effective follow-up.

关 键 词：男男性行为者 丙肝病毒 干预研究 随访 

分 类 号：R512.63[医药卫生—内科学]