不同时期新型冠状病毒感染者感染途径分析  

Analysis of infection routes among SARS-CoV-2 infected patients within different periods

作　　者：田祎[1] 李爽[1] 王鑫馨 张莉[1] 吴晓娜[1] 马春娜[1] 陈艳伟[1] 张代涛[1] 王全意[1] 贾蕾[1] Tian Yi;Li Shuang;Wang Xinxin;Zhang Li;Wu Xiaona;Ma Chunna;Chen Yanwei;Zhang Daitao;Wang Quanyi;Jia Lei(Institute for Infectious Disease and Endemic Disease Prevention and Control,Beijing Center for Disease Prevention and Control,Beijing 100013,China;School of Public Health,Capital Medical University,Beijing 100069,China)

机构地区：[1]北京市疾病预防控制中心传染病地方病控制所,100013 [2]首都医科大学公共卫生学院,北京100069

出　　处：《国际病毒学杂志》2023年第5期388-392,共5页International Journal of Virology

基　　金：北京市科技计划项目(Z221100007922020)。

摘　　要：目的分析不同时期新型冠状病毒感染者感染途径,为进一步做好疫情监测工作提供参考。方法分层抽取2022年12月8日至31日和2023年2月1日至24日新型冠状病毒感染者,分析感染前5 d接触重点人群、近距离接触有新冠症状或新冠感染阳性人员情况以及到访场所等。使用SPSS 20.0软件进行统计分析,计数资料组间比较采用卡方检验,计量资料采用Wilcoxon秩和检验,比较两次调查新型冠状病毒感染者感染途径是否存在差异。结果两次调查分别纳入新冠感染者191例和199例。两次调查感染者感染前5 d 2米内是否接触重点人群比较,差异无统计学意义(χ^(2)=0.792,P=0.373),均为接触过快递员的占比最高。第一次调查的感染者中,感染前5 d 2米内面对面接触的人中有新冠相关症状者比例(61.78%,118/191)高于第二次调查(48.24%,96/199),差异有统计学意义(χ^(2)=7.752,P=0.005)。第一次调查的感染者中,感染前5 d 2米内面对面接触的人中有新冠阳性人员的比例(62.83%,120/191)高于第二次调查(46.73%,93/199),差异有统计学意义(χ^(2)=10.184,P=0.001)。接触的有新冠相关症状人员和新冠阳性人员,均为同住人员的占比最高。第二次调查的感染者到访过场所个数多于第一次,差异有统计学意义(Z=-5.025,P<0.01)。结论两次调查中北京市新冠感染者感染途径均以密切接触有新冠相关症状和(或)新型冠状病毒阳性人员为主。第二次调查中人群社会活动明显增多,传播更具有隐匿性,应持续做好疫情监测、预警工作,及早发现疫情。Objective To analyze the infection routes of patients infected with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)during different periods,so as to provide a reference for further epidemic surveillance.Methods SARS-CoV-2 infected patients from December 8 to 31,2022,and from February 1 to 24,2023 were stratified and sampled.The contacting with key populations,closely contacting with people who had symptoms or were positive for SARS-CoV-2 within 5 d before infection,as well as the visited places were analyzed.SPSS 20.0 was used for statistical analysis.The chi-square test was used for comparison the count data in the groups.Wilcoxon rank-sum test was used for measurement data in the groups.The differences in infection routes of SARS-CoV-2 between the two surveys were compared.Results In the two surveys,there were 191 and 199 SARS-CoV-2 infected patients enrolled respectively.The difference between patients who had contact and no-contact within the range of 2 m with key population in 5 d before infection was not statistically significant(χ^(2)=0.792,P=0.373).Couriers accounted for the highest proportions for both groups of patients.The proportion of patients in the first survey(61.78%,118/191)who had face-to-face contact in a range of 2 m with people with SARS-CoV-2 related symptoms within 5 d before infection was higher than that of the second survey(48.24%,96/199).The difference was statistically significant(χ^(2)=7.752,P=0.005).The proportion of patients in the first survey(62.83%,120/191)who had face-to-face contact in a range of 2 m with SARS-CoV-2 positive persons within 5 days was higher than that in the second survey(46.73%,93/199).The difference was statistically significant(χ^(2)=10.184,P=0.001).The proportions of contacting by cohabitation with people with SARS-CoV-2 related symptoms or SARS-CoV-2 positive persons were the highest in both groups of patients.The number of visited places in the second survey was higher than that in the first survey and The difference was statistically signif

关 键 词：新型冠状病毒 感染者 感染途径 

分 类 号：R563.1[医药卫生—呼吸系统]