基于“肾生髓通脑”理论探析补肾方药在认知障碍中的应用  

Exploring the Application of Kidney-Tonifying Prescriptions in Cognitive Impairment Based on the Theory of Kidney Generating Marrow and Unblocking Brain Collaterals

作　　者：李欣宁 施圣杰 沈劼 董宇[2] LI Xin-ning;SHI Sheng-jie;SHEN Jie;DONG Yu(Institute of Literature in Chinese Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学中医药文献研究所,江苏南京210023 [2]南京中医药大学药学院,江苏南京210023

出　　处：《南京中医药大学学报》2023年第11期1070-1075,共6页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金项目(82004224)。

摘　　要：系统阐述了“肾生髓通脑”的理论内涵,指出肾、髓、脑在结构和功能上的联系。认为脑髓失充为认知障碍发病的关键,肾虚贯穿于认知障碍始终,痰、瘀为其重要病理因素,治疗当以补肾为主,通过补肾法以充养脑髓,健脑强志,祛痰化瘀,提出补肾阳和补肾阴的代表方药,为临床防治认知障碍及拓展其选方用药提供思路和方法。This paper systematically expounds the research advance and theoretical connotation of the kidney generating the marrow and unblocking brain collaterals,and points out the relationship between the kidney,marrow and brain in terms of structure and function.The article proposes that brain marrow insufficiency is the key to the onset of cognitive impairment.Kidney deficiency runs through cognitive impairment,and phlegm and blood stasis are important pathological factors.The treatment should mainly focus on tonifying the kidney.Through the kidney-tonifying method,the purposes of nourishing the brain and marrow,strengthening the brain and memory,and helping to eliminate phlegm and remove blood stasis are proposed.Representative prescriptions for tonifying kidney yang and kidney yin are proposed to provide ideas and methods for the clinical prevention and treatment of cognitive impairment and the expansion of its prescription and medication selection.

关 键 词：认知障碍 肾生髓通脑 补肾法 临床应用 

分 类 号：R289.56[医药卫生—方剂学]