发泡胶对鼻咽癌调强放疗计划的剂量学影响  

Dosimetric Effect of Styrofoam on Intensity-Modulated Radiotherapy for Nasopharyngeal Carcinoma

作　　者：陈善凤[1] 叶铭兰 梁少杰 谭俊昌 江国文[1] 陈伙辉 黄家满 CHEN Shanfeng;YE Minglan;LIANG Shaojie;TAN Junchang;JIANG Guowen;CHEN Huohui;HUANG Jiaman(Department of Radiation Physics and Technology,The Second People’s Hospital of Zhaoqing,Zhaoqing Guangdong 526300,China)

机构地区：[1]肇庆市第二人民医院放疗物理技术科,广东肇庆526300

出　　处：《中国医疗设备》2023年第12期74-79,共6页China Medical Devices

摘　　要：目的 探讨发泡胶对鼻咽癌调强放射治疗计划的剂量学影响。方法 首先测量发泡胶不同厚度对中心点剂量的影响。然后选取11例使用头颈肩热塑膜联合发泡胶进行体位固定的早期鼻咽癌患者,对每例患者勾画两种外轮廓,一种勾画人体正常皮肤外轮廓,另一种将发泡胶也勾画进人体外轮廓。分别设计两种不同皮肤外轮廓的调强计划,比较两种计划的靶区剂量、危及器官剂量和皮肤剂量。结果 将发泡胶加入外轮廓后,降低了鼻咽癌放疗计划的靶区剂量和危及器官的剂量,靶区最大剂量降低了0.56%~0.78%,靶区平均剂量分别降低了0.63%~0.90%。脊髓、视交叉、视神经等危及器官的最大剂量降低了0.2%~1.1%。颈后皮肤平均剂量增加0.8~6.0 Gy。结论 发泡胶的应用降低了鼻咽癌调强计划的靶区剂量和危及器官剂量,增加了皮肤剂量。Objective To study the dosimetric effect of styrofoam on intensity-modulated radiotherapy for nasopharyngeal carcinoma.Methods Firstly,the effect of different thickness of styrofoam on the central point dose was measured.Then 11 patients with early nasopharyngeal carcinoma who were fixed with head-neck-shoulder thermoplastic mask combined with styrofoam were selected,two outer contours were drawn for each patient,one sketched the outer contour of normal human skin,and the other sketched the styrofoam into the outer contour of human body.Two kinds of intensity modulation plans with different skin contours were designed,the target dose,organ at risk dose and skin dose of the two plans were compared.Results After adding the styrofoam to the outer contour,the target dose and the dose of the organ at risk of the nasopharyngeal carcinoma intensity modulated radioeheropy plan were reduced.The maximum dose of the target area was reduced by 0.56%-0.78%,and the average dose was reduced by 0.63%-0.90%.The maximum doses to the spinal cord,optic chiasm,optic nerve and other organs at risk were reduced by 0.2%-1.1%.The average dose of posterior cervical skin increased about 0.8-6.0 Gy.Conclusion The application of styrofoam reduced the target dose and organ at risk dose of nasopharyngeal carcinoma intensity-modulated plan,and increased the skin dose.

关 键 词：发泡胶 鼻咽癌 调强放疗 剂量学 皮肤剂量 

分 类 号：R318.6[医药卫生—生物医学工程]